ArticleMedical oncology (Northwood, London, England)2011
Body mass index and waist circumference are predictor biomarkers of breast cancer risk in Iranian women.
Article in Medical oncology (Northwood, London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Systematic Review and Meta-Analysis of Lifestyle and Reproductive Factors Associated with Risk of Breast Cancer in Asian Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Pooled it
- Obesity has multifaceted impact on biochemical recurrence of prostate cancer: a dose-response meta-analysis of 36,927 patients.Medical oncology (Northwood, London, England) · 2014Pooled it
- Accuracy of self-perceived risk perception of breast cancer development in Iranian women.BMC women's health · 2021Article
- Medical Diagnostic Tests: A Review of Test Anatomy, Phases, and Statistical Treatment of Data.Computational and mathematical methods in medicine · 2019Review
- Comparison of pathologic characteristics of breast cancer in younger and older women.Caspian journal of internal medicine · 2019Article
- Levels of C-reactive protein, creatine kinase-muscle and aldolase A are suitable biomarkers to detect the risk factors for osteoarthritic disorders: A novel diagnostic protocol.Caspian journal of internal medicine · 2019Article
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- Fibroblast growth factor receptor is a mechanistic link between visceral adiposity and cancer.Oncogene · 2017Article
- Impact of obesity upon prostate cancer-associated mortality: A meta-analysis of 17 cohort studies.Oncology letters · 2015Article
- Specific TaqMan allelic discrimination assay for rs1477196 and rs9939609 single nucleotide polymorphisms of FTO gene demonstrated that there is no association between these SNPs and risk of breast cancer in Iranian women.Advanced biomedical research · 2015Article
- Effect of 8-week nutrition counseling to increase phytochemical rich fruit and vegetable consumption in korean breast cancer patients: a randomized controlled trial.Clinical nutrition research · 2014Article
- Receiver Operating Characteristic (ROC) Curve Analysis for Medical Diagnostic Test Evaluation.Caspian journal of internal medicine · 2013Review
- Synthetic adipose tissue models for studying mammary gland development and breast tissue engineering.Journal of mammary gland biology and neoplasia · 2010Review
- Performance Characteristics of Kidney Injury Molecule-1 In Relation to Creatinine, Urea, and Microalbuminuria in the Diagnosis of Kidney Disease.International journal of applied & basic medical researchArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Both obesity and breast cancer incidence increased dramatically during two recent decades in a rapidly changing society in northern Iran. In this study, we examined the ability of body mass index (BMI) and waist circumference (WC) as predictor biomarkers of breast cancer risk in Iranian women. In a case-control study of 100 new cases of histological confirmed breast cancer and 200 age-matched controls, in Babol, we measured weight, height, waist and hip circumference at time of diagnosis with standard methods. The data of demographic, characteristics, reproductive and lifestyle factors were collected by interview. We used both regression and receiver operator characteristics (ROC) analysis to estimate the predictive ability of BMI and WC for breast cancer as estimated by area under the curve (AUC). The results showed a significant difference in the mean of weight, BMI and WC between patients and controls in pre- and postmenopausal women (P<0.001). While after adjusting for BMI, no longer an association between WC and breast cancer was found. The overall accuracy of observed BMI and WC were 0.79 (95% CI: 0.74-0.84) and 0.68 (95% CI: 0.61-0.74), respectively. The accuracy of BMI and WC were 0.82 (95% CI: 0.76-0.89), 0.75(0.67-0.83) for premenopausal and 0.77(0.68-0.85), 0.60 (0.50-0.71) for postmenopausal women, respectively. BMI and WC are predictor biomarkers of breast cancer risk in both pre- and postmenopausal Iranian women while after adjusting for BMI, no longer an association between WC and breast cancer was observed. These findings imply to perform breast cancer screening program in women with a higher BMI and WC.
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