ATRIP from TopBP1 to ATR--in vitro activation of a DNA damage checkpoint.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. Transient caspase-mediated activation of caspase-activated DNase causes DNA damage required for phagocytic macrophage differentiation.Cell reports · 2024
   Article
2. Duox-generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest ineLife · 2021
   Article
3. Replication and ribosomal stress induced by targeting pyrimidine synthesis and cellular checkpoints suppress p53-deficient tumors.Cell death & disease · 2020
   Article
4. Why Human Papillomaviruses Activate the DNA Damage Response (DDR) and How Cellular and Viral Replication Persists in the Presence of DDR Signaling.Viruses · 2017
   Review
5. A physical association between the human mutY homolog (hMYH) and DNA topoisomerase II-binding protein 1 (hTopBP1) regulates Chk1-induced cell cycle arrest in HEK293 cells.Cell & bioscience · 2015
   Article
6. MicroRNA binding site polymorphisms as biomarkers in cancer management and research.Pharmacogenomics and personalized medicine · 2014
   Review
7. Clamping down on mammalian meiosis.Cell cycle (Georgetown, Tex.) · 2013
   Article
8. Association between the c.*229C>T polymorphism of the topoisomerase IIβ binding protein 1 (TopBP1) gene and breast cancer.Molecular biology reports · 2013
   Article
9. Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance.PLoS genetics · 2013
   Article
10. Replication fork stalling and checkpoint activation by a PKD1 locus mirror repeat polypurine-polypyrimidine (Pu-Py) tract.The Journal of biological chemistry · 2012
    Article
11. The phosphorylation network for efficient activation of the DNA replication checkpoint in fission yeast.The Journal of biological chemistry · 2011
    Article

Corrections and comments

• Comment on
  Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling.2010

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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