ArticleProceedings of the National Academy of Sciences of the United States of America2010
Pore turret of thermal TRP channels is not essential for temperature sensing.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Thermodynamic coupling between cold and heat activations of TRPV2.Scientific reports · 2026Article
- Mechanism of lipid-dependent cold sensitivity in a model ion channel.Nature communications · 2026Article
- Temperature-dependent gating pathways in TRPV3.Scientific reports · 2026Article
- Pathway-dependent cold activation of heat-responsive TRPV channels.Scientific reports · 2025Article
- A molecular perspective on identifying TRPV1 thermosensitive regions and disentangling polymodal activation.Temperature (Austin, Tex.) · 2023Review
- Structural mechanisms of transient receptor potential ion channels.The Journal of general physiology · 2020Review
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- TRPV1 temperature activation is specifically sensitive to strong decreases in amino acid hydrophobicity.Scientific reports · 2017Article
- Single-residue molecular switch for high-temperature dependence of vanilloid receptor TRPV3.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Temperature-sensitive gating of TRPV1 channel as probed by atomistic simulations of its trans- and juxtamembrane domains.Scientific reports · 2016Article
- Article
- Temperature and voltage coupling to channel opening in transient receptor potential melastatin 8 (TRPM8).The Journal of biological chemistry · 2014Article
- Mutation of I696 and W697 in the TRP box of vanilloid receptor subtype I modulates allosteric channel activation.The Journal of general physiology · 2014Article
- Structure of thermally activated TRP channels.Current topics in membranes · 2014Review
- High-resolution views of TRPV1 and their implications for the TRP channel superfamily.Handbook of experimental pharmacology · 2014Review
- The role of endogenous molecules in modulating pain through transient receptor potential vanilloid 1 (TRPV1).The Journal of physiology · 2013Review
- Single residues in the outer pore of TRPV1 and TRPV3 have temperature-dependent conformations.PloS one · 2013Article
- Expression-dependent pharmacology of transient receptor potential vanilloid subtype 1 channels in Xenopus laevis oocytes.Channels (Austin, Tex.) · 2013Article
- Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations.The Journal of general physiology · 2012Article
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3 authors.
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Abstract
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.