ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2010
Feeding-mediated distention inhibits swimming in the medicinal leech.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
- Descending GABAergic pathway links brain sugar-sensing to peripheral nociceptive gating in Drosophila.Nature communications · 2023Article
- MDN brain descending neurons coordinately activate backward and inhibit forward locomotion.eLife · 2018Article
- Octopamine and Tyramine Contribute Separately to the Counter-Regulatory Response to Sugar Deficit inFrontiers in systems neuroscience · 2017Article
- Responses to conflicting stimuli in a simple stimulus-response pathway.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Multiplexed modulation of behavioral choice.The Journal of experimental biology · 2014Article
- Detection and selective avoidance of near ultraviolet radiation by an aquatic annelid: the medicinal leech.The Journal of experimental biology · 2014Article
- A pair of interneurons influences the choice between feeding and locomotion in Drosophila.Neuron · 2013Article
- Decision points: the factors influencing the decision to feed in the medicinal leech.Frontiers in neuroscience · 2012Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
An animal's response to a stimulus depends on many factors such as age, hormonal state, experience, and its behavioral state. For example, an animal may suppress a behavior that is inappropriate or incompatible with its current state. In this study, we show that, as a medicinal leech feeds, the distention that it incurs inhibits its expression of swimming. Distention slows the swimming pattern and decreases the number of swim cycles elicited by a test electrical stimulation; large distentions inhibit swimming altogether. We have previously shown that the ingestive phase of feeding inhibits behaviors by presynaptic inhibition of mechanosensory neurons. Distention has its effects downstream (e.g., gating and central pattern generating interneurons) from these sensory neurons and thus represents a novel mechanism for choosing between conflicting behaviors during feeding. Because removing the leech's gut surgically did not eliminate the effects of body distention, we conclude that the receptors mediating the distention-induced suppression of swimming are likely to be located in the animal's body wall. Together with previous findings, these new data show that leeches rely on two different decision-making networks to ensure that a biologically important behavior is not disrupted by other behaviors.
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