ArticleJournal of clinical microbiology2010
Diagnosis of canine vector-borne diseases in young dogs: a longitudinal study.
Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it, 120 citations in OpenAlex.
- World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence-Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis.Veterinary dermatology · 2025Guideline
- Field Evaluation of Two Different Treatment Approaches and Their Ability to Control Fleas and Prevent Canine Leishmaniosis in a Highly Endemic Area.PLoS neglected tropical diseases · 2016Trial
- Evaluation of a Point-of-Care Multiplex PCR Analyser for Detection ofVeterinary sciences · 2026Article
- Comparative efficacy of once-daily versus twice-daily doxycycline regimens in dogs naturally infected withVeterinary and animal science · 2026Article
- Canine Leishmaniosis in Liguria, Northwest Italy: A Nine-Year Retrospective Study in a Historically Endemic Area.Animals : an open access journal from MDPI · 2026Article
- Canine vector-borne diseases: a changing world demands a new preventive strategy from veterinarians.Parasites & vectors · 2026Review
- Prevalence ofPathogens (Basel, Switzerland) · 2025Article
- Comparative analysis of diagnostic methods and genetic analysis for canine vector-borne diseases in Thailand.Scientific reports · 2025Article
- Concurrent infection ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025Article
- First Case of Human Ocular Dirofilariasis in the Aosta Valley Region: Clinical Management and Morphological-Molecular Confirmation.Pathogens (Basel, Switzerland) · 2025Article
- Molecular survey of tick-borne pathogens in domestic dogs from a rural region within the buffer zone of a conservation unit in the Brazilian Caatinga biome.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2025Article
- Molecular and microscopic detection of haemoprotozoan diseases in dogs from Haryana, India.Parasitology research · 2024Article
- First Evidence ofVeterinary sciences · 2024Article
- Leishmania spp. in equids and their potential vectors in endemic areas of canine leishmaniasis.PLoS neglected tropical diseases · 2024Article
- The first report of Dirofilaria repens infection in dogs from Colombia.Parasitology research · 2023Article
- Co-infection patterns of vector-borne zoonotic pathogens in owned free-ranging dogs in central Chile.Veterinary research communications · 2023Article
- Epidemiological Survey on Tick-Borne Pathogens with Zoonotic Potential in Dog Populations of Southern Ethiopia.Tropical medicine and infectious disease · 2023Article
- Editorial: Dog filariosis: the threat walks not only in the blood stream.Frontiers in veterinary science · 2023Article
- Leishmania (Sauroleishmania) tarentolae isolation and sympatric occurrence with Leishmania (Leishmania) infantum in geckoes, dogs and sand flies.PLoS neglected tropical diseases · 2022Article
- Prevalence ofVeterinary world · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Canine vector-borne diseases (CVBDs) pose a diagnostic challenge, particularly when a dog is coinfected with more than one pathogen. The purpose of this study was to generate information about the diagnosis of CVBDs in young dogs following their first exposure to flea, tick, sand fly, louse, and mosquito vectors. From March 2008 to May 2009, 10 purpose-bred young naive beagle dogs and a cohort of 48 mixed-breed dogs living in an area to which CVBD is endemic in southern Italy were monitored using different diagnostic tests (cytology, serology, and PCR). Overall, PCR detected the highest number of dogs infected with Anaplasma platys, Babesia vogeli, and Ehrlichia canis, whereas seroconversion was a more sensitive indicator of exposure to Leishmania infantum. For A. platys infection, combining blood and buffy coat cytology in parallel enhanced the relative sensitivity (SE(rel)) (87.3%). For B. vogeli, the best diagnostic combination was buffy coat cytology and serology used in parallel (SE(rel), 67.5%), whereas serology and PCR used in parallel (SE(rel), 100%) was the best combination for L. infantum. Overall, 12 (20.7%) dogs were coinfected; however, the percentage of new coinfections decreased from baseline (50%) to the first (33.3%) and second (16.6%) follow-up time points. Numbers of coinfections with A. platys and B. vogeli were significantly higher (P < 0.05) than coinfections with other pathogen combinations. The data generated in this study provide insights on the incidence of certain pathogens infecting young dogs in southern Italy, highlight important diagnostic testing limitations, and support the use of multiple diagnostic modalities when attempting to confirm a tick-borne infection in an individual dog or in a canine population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.