ArticleJournal of occupational medicine and toxicology (London, England)2010
Results of five-year systematic screening for latent tuberculosis infection in healthcare workers in Portugal.
Article in Journal of occupational medicine and toxicology (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 31 citations in OpenAlex.
- The Interferon-Gamma Release Assay versus the Tuberculin Skin Test in the Diagnosis ofVaccines · 2023Article
- Infections in Healthcare Workers in Germany-22-Year Time Trends.International journal of environmental research and public health · 2018Article
- Interferon-gamma release assay for the diagnosis of latent tuberculosis infection: A latent-class analysis.PloS one · 2017Article
- Prevalence of latent tuberculosis infection in healthcare workers at a hospital in Naples, Italy, a low-incidence country.Journal of occupational medicine and toxicology (London, England) · 2016Article
- Prevalence of latent tuberculosis infection and associated risk factors among 1557 nursing students in a context of low endemicity.The open nursing journal · 2015Article
- Prevalence of latent tuberculosis infection and associated risk factors among 3,374 healthcare students in Italy.Journal of occupational medicine and toxicology (London, England) · 2014Article
- Optimizing the protection of research participants and personnel in HIV-related research where TB is prevalent: practical solutions for improving infection control.Journal of acquired immune deficiency syndromes (1999) · 2014Article
- Latent tuberculosis in healthcare workers: time to act.Oman medical journal · 2013Article
- Screening for tuberculosis and the use of a borderline zone for the interpretation of the interferon-γ release assay (IGRA) in Portuguese healthcare workers.Journal of occupational medicine and toxicology (London, England) · 2013Article
- Latent tuberculosis infection screening for laboratory personnel using interferon-γ release assay and tuberculin skin test in Korea: an intermediate incidence setting.Journal of clinical laboratory analysis · 2011Article
- Screening for tuberculosis and prediction of disease in Portuguese healthcare workers.Journal of occupational medicine and toxicology (London, England) · 2011Article
- Latent tuberculosis in nursing professionals of a Brazilian hospital.Journal of occupational medicine and toxicology (London, England) · 2011Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe risk of tuberculosis (TB) in healthcare workers (HCWs) is related to its incidence in the general population, and increased by the specific risk as a professional group. The prevalence of latent tuberculosis infection (LTBI) in HCWs in Portugal using the tuberculin skin test (TST) and the interferon-gamma release assays (IGRA) was analyzed over a five-year period.
methodsA screening programme for LTBI in HCWs was conducted, with clinical evaluations, TST, IGRA, and chest radiography. Putative risk factors for LTBI were assessed by a standardised questionnaire.
resultsBetween September 2005 and June 2009, 5,414 HCWs were screened. The prevalence of LTBI was 55.2% and 25.9% using a TST >/= 10 mm or an IGRA test result (QuantiFERON-TB Gold In-Tube) INF-gamma >/=0.35 IU/mL as a criterion for LTBI, respectively. In 53 HCWs active TB was diagnosed. The number of HCWs with newly detected active TB decreased from 19 in the first year to 6 in 2008. Risk assessment was poorly related to TST diameter. However, physicians (1.7%) and nurses (1.0%) had the highest rates of active TB.
conclusionsLTBI and TB burden among HCWs in Portugal is high. The screening of these professionals to identify HCWs with LTBI is essential in order to offer preventive chemotherapy to those with a high risk of future progression to disease. Systematic screening had a positive impact on the rate of active TB in HCWs either by early case detection or by increasing the awareness of HCWs and therefore the precautions taken by them.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.