ArticleDrugs & aging2010
Treatment with fall-risk-increasing and fracture-preventing drugs before and after a hip fracture: an observational study.
Article in Drugs & aging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01627483 (Improving Treatment With Fracture-preventing and Fall-risk-increasing Drugs in Older Hip Fracture Patients), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improving Treatment With Fracture-preventing and Fall-risk-increasing Drugs in Older Hip Fracture Patients: Effects of Medication Reviews Performed by a Physician - a Randomized Controlled Trial
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Potentially inappropriate prescribing and falls-risk increasing drugs in people who have experienced a fall: a systematic review and meta-analysis.Age and ageing · 2025Pooled it
- Use of Fall Risk-Increasing Drugs Around a Fall-Related Injury in Older Adults: A Systematic Review.Journal of the American Geriatrics Society · 2020Pooled it
- Patterns of drug prescriptions in an orthogeriatric ward as compared to orthopaedic ward: results from the Trondheim Hip Fracture Trial-a randomised clinical trial.European journal of clinical pharmacology · 2017Trial
- Association between drug-specific indicators of prescribing quality and quality of drug treatment: a validation study.Pharmacoepidemiology and drug safety · 2015Trial
- The Use of Direct Oral Anticoagulants (DOACs) in Older Adults Receiving Multidose Drug Dispensing; Interactions, Anticholinergic and Fall-Risk Increasing Drugs.Geriatrics (Basel, Switzerland) · 2026Article
- Falls and Fractures Among Medicare Beneficiaries Concurrently Receiving Anti-Dementia Drugs and Potentially Risky Medications.Medical care · 2025Article
- Deprescribing psychoactive drugs in older orthogeriatric patients: findings from the GIOG2.0 Italian survey.BMC geriatrics · 2025Observational
- Prevalence of fall risk-increasing drugs in older adults presenting with falls to the emergency department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2023Article
- Development and Pilot Testing of a Booklet Concerning Medications That Can Increase the Risk of Falls in Older People.International journal of environmental research and public health · 2022Article
- Review
- Change in central nervous system-active medication use following fall-related injury in older adults.Journal of the American Geriatrics Society · 2022Article
- Prevalence of medication-related falls in 200 consecutive elderly patients with hip fractures: a cross-sectional study.BMC geriatrics · 2020Article
- Orthogeriatric treatment reduces potential inappropriate medication in older trauma patients: a retrospective, dual-center study comparing conventional trauma care and co-managed treatment.European journal of medical research · 2019Article
- Fall-risk increasing drugs and recurrent injurious falls association in older patients after hip fracture: a cohort study protocol.Therapeutic advances in drug safety · 2019Article
- Comorbidities and medication use in patients with a recent clinical fracture at the Fracture Liaison Service.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Article
- Falls-Related Drug Use and Risk of Falls Among Older Adults: A Study in a US Medicare Population.Drugs & aging · 2017Article
- Clinical relevance of the STOPP/START criteria in hip fracture patients.European journal of clinical pharmacology · 2017Article
- Patterns of Prescription Drug Use Before and After Fragility Fracture.JAMA internal medicine · 2016Article
- Number of drugs in the medication list as an indicator of prescribing quality: a validation study of polypharmacy indicators in older hip fracture patients.European journal of clinical pharmacology · 2015Article
- Prevalence of suboptimal drug treatment in patients with and without multidose drug dispensing--a cross-sectional study.European journal of clinical pharmacology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHip fracture is a common diagnosis in the older population, with often serious consequences. Drug treatment may be of significance for both falls and fractures.
objectiveTo investigate drug treatment in older hip fracture patients, focusing on use of fall-risk-increasing and fracture-preventing drugs before and after the fracture.
methodsThis was an observational study conducted in Sahlgrenska University Hospital, Gothenburg, Sweden. The participants were 100 consecutive hip fracture patients aged > or =65 years with a median age of 86 (range 66-97) years. Seventy-three patients were female, and 87 patients had at least one strong risk factor for a fracture. Four patients died during the hospital stay, and a further 18 died within 6 months after discharge. Treatment with fall-risk-increasing and fracture-preventing drugs at admission to hospital, at discharge and 6 months after the hip fracture was measured.
resultsThe numbers of patients treated with fall-risk-increasing drugs were 93 (93%), 96 (100%) and 73 (94%) at admission, discharge and 6-month follow-up, respectively. The median (range) number of such drugs was 3 (0-9), 4 (1-10) and 3 (0-10), respectively. A total of 17 (17%), 32 (33%) and 29 (37%) patients were treated with fracture-preventing drugs, predominantly calcium plus vitamin D, at admission, discharge and 6-month follow-up, respectively. Five patients (5%) used bisphosphonates or selective estrogen receptor modulators at admission. No additional patients had these drugs prescribed during the hospital stay. At 6-month follow-up, four more patients were treated with bisphosphonates.
conclusionsTreatment with fall-risk-increasing drugs was extensive among older hip fracture patients both before and after the fracture. The proportion of patients with fracture-preventing drugs was low at admission and increased slightly during the follow-up period. Hence, drug treatment in older hip fracture patients can be improved regarding both fall-risk-increasing drugs and fracture-preventing drugs.
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