ArticleMedical & biological engineering & computing2010
A robust sliding mode controller with internal model for closed-loop artificial pancreas.
Article in Medical & biological engineering & computing, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 28 citations in OpenAlex.
- Modelling the effect of insulin on the disposal of meal-attributable glucose in type 1 diabetes.Medical & biological engineering & computing · 2017Article
- Designing an artificial pancreas architecture: the AP@home experience.Medical & biological engineering & computing · 2015Article
- Evaluation of short-term predictors of glucose concentration in type 1 diabetes combining feature ranking with regression models.Medical & biological engineering & computing · 2015Article
- A mechanical chest compressor closed-loop controller with an effective trade-off between blood flow improvement and ribs fracture reduction.Medical & biological engineering & computing · 2015Article
- Multilevel model of type 1 diabetes mellitus patients for model-based glucose controllers.Journal of diabetes science and technology · 2013Article
- Non-invasive continuous glucose monitoring: improved accuracy of point and trend estimates of the Multisensor system.Medical & biological engineering & computing · 2012Article
- Stabilized glucagon formulation for bihormonal pump use.Journal of diabetes science and technology · 2010Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study presents a robust closed-loop sliding mode controller with internal model for blood glucose control in type-1 diabetes. Type-1 diabetic patients depend on external insulin delivery to keep their blood glucose within near-normal ranges. Closed-loop artificial pancreas is developed to help avoid dangerous, potentially life-threatening hypoglycemia, as well as to prevent complication-inducing hyperglycemia. The proposed controller is designed using a combination of sliding mode and internal model control techniques. To enhance postprandial performance, a feedforward controller is added to inject insulin bolus. Simulation studies have been performed to test the controller, which revealed that the proposed control strategy is able to control the blood glucose well within the safe limits in the presence of meals and measurements errors. The controller shows acceptable robustness against changes in insulin sensitivity, model-patient mismatch, and errors in estimating meal's contents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.