Evidence map›Paper›PMID 20658245›Full record

ArticleJournal of neurology2011

Coping style and quality of life in patients with epilepsy: a cross-sectional study.

Willemien Westerhuis, Maeike Zijlmans, Kathelijn Fischer, Judith van Andel, Frans S S Leijten

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of neurology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05450822 (The BrainDrugs-Epilepsy Study), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05450822 recruitingnot on this mapstarted 2022, after this paper: background citation

The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy

TypeobservationalSponsorGitte Moos KnudsenRan2022 to 2031Enrolled550ConditionsEpilepsyArmsLevetiracetam, Levetiracetam Tablets, Lamotrigine tablet
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
  2. Article
  3. Coping strategies and quality of life in patients with chronic symptoms visiting a Lyme Center in a Dutch teaching hospital.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
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  5. Review
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  16. Advances in Hereditary Angioedema: The Prevention of Angioedema Attacks With Subcutaneous C1-Inhibitor Replacement Therapy.Journal of infusion nursing : the official publication of the Infusion Nurses Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Willemien WesterhuisDepartment of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands.
Maeike Zijlmans
Kathelijn Fischer
Judith van Andel
Frans S S Leijten
University Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Having epilepsy has a large impact on one's well-being, but often seizure frequency and severity do not explain self-reported quality of life. We hypothesized that one's personal coping style is more important. In this study, 105 patients attending the outpatient neurological clinic at the University Medical Centre in Utrecht, the Netherlands, with a diagnosis of partial epilepsy, aged 17-80 years, completed questionnaires. Demographic information, disease characteristics, health-related quality of life (HRQoL), and coping styles were obtained by postal-validated HRQoL questionnaires: the EQ5D and RAND-36 and the Utrecht Coping List. A passive coping style explained 45% of the variance in the mental component of HRQoL and was more important than 'objective' seizure-related measures. Confounders such as employment, gender, and side-effects of treatment explained another 6%. Passive coping style also influenced the physical component of the HRQoL, but here seizure-related factors predominated. Overall, epilepsy patients showed a more avoiding coping style, and female patients a less active coping style and more reassuring thoughts, compared to the Dutch population. The personal coping style of patients appears to be more important than seizure-related measures in predicting mental aspects of quality of life. Coping style characteristics rather than disease characteristics should guide clinical decision-making in patients with epilepsy. Further studies should investigate the effect on HRQoL of behavioral interventions to improve coping.

Indexed as

Adaptation, PsychologicalQuality of LifeAdolescentAdultAgedAged, 80 and overCross-Sectional StudiesEpilepsyFemaleHumansMaleMiddle AgedNetherlandsSeizuresSex FactorsSocioeconomic Factors

Identifiers

PMID20658245
PMCPMC3016152
OpenAlexW2107899189

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.