ArticleNanotechnology2010
Detection of DNA hybridizations using solid-state nanopores.
Article in Nanotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Decoding information stored in DNAs through single-molecule electrical detection platforms.Innovation (Cambridge (Mass.)) · 2025Review
- Detection and Separation of DNA and Silver Nanoparticles Using a Solid-State Nanopore.ACS omega · 2023Article
- Sequence-Specific Detection of DNA Strands Using a Solid-State Nanopore Assisted by Microbeads.Micromachines · 2020Article
- Osmotically Driven and Detected DNA Translocations.Scientific reports · 2019Article
- Differentiation of G:C vs A:T and G:C vs G:mC Base Pairs in the Latch Zone of α-Hemolysin.ACS nano · 2015Article
- The evolution of nanopore sequencing.Frontiers in genetics · 2014Review
- On the distribution of DNA translocation times in solid-state nanopores: an analysis using Schrödinger's first-passage-time theory.Journal of physics. Condensed matter : an Institute of Physics journal · 2013Article
- An electro-hydrodynamics-based model for the ionic conductivity of solid-state nanopores during DNA translocation.Nanotechnology · 2013Article
- Sequence-specific nucleic acid detection from binary pore conductance measurement.Journal of the American Chemical Society · 2012Article
- Landscape of next-generation sequencing technologies.Analytical chemistry · 2011Review
- The properties and applications of single-molecule DNA sequencing.Genome biology · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
We report an experimental study of using DNA translocation through solid-state nanopores to detect the sequential arrangement of two double-stranded 12-mer hybridization segments on a single-stranded DNA molecule. The sample DNA is a trimer molecule formed by hybridizing three single-stranded oligonucleotides. A polystyrene bead is attached to the end of the trimer DNA, providing a mechanism in slowing down the translocation and suppressing the thermal diffusion, thereby allowing the detection of short features of DNA by standard patch-clamp electronics. The electrical signature of the translocation of a trimer molecule through a nanopore has been identified successfully in the temporal traces of ionic current. The results reported here represent the first successful attempt in using a solid-state nanopore as an ionic scanning device in resolving individual hybridization segments (or 'probes') on a DNA molecule.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.