ArticleApplied and environmental microbiology2010
A population genetics-based and phylogenetic approach to understanding the evolution of virulence in the genus Listeria.
Article in Applied and environmental microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Human Listeriosis.Clinical microbiology reviews · 2023Review
- Salmonella Prevalence Is Strongly Associated with Spatial Factors while Listeria monocytogenes Prevalence Is Strongly Associated with Temporal Factors on Virginia Produce Farms.Applied and environmental microbiology · 2023Article
- Whole-genome sequencing ofFrontiers in microbiology · 2023Article
- Comparison of Resampling Algorithms to Address Class Imbalance when Developing Machine Learning Models to Predict Foodborne Pathogen Presence in Agricultural Water.Frontiers in environmental science · 2021Article
- Landscape, Water Quality, and Weather Factors Associated With an Increased Likelihood of Foodborne Pathogen Contamination of New York Streams Used to Source Water for Produce Production.Frontiers in sustainable food systems · 2020Article
- Large-Scale Comparison of Toxin and Antitoxins inToxins · 2020Article
- The Composition of Microbial Communities in Six Streams, and Its Association With Environmental Conditions, and Foodborne Pathogen Isolation.Frontiers in microbiology · 2020Article
- Complex Interactions Between Weather, and Microbial and Physicochemical Water Quality Impact the Likelihood of Detecting Foodborne Pathogens in Agricultural Water.Frontiers in microbiology · 2020Article
- Atypical HemolyticInfection and immunity · 2019Article
- A Simple and Robust Statistical Method to Define Genetic Relatedness of Samples Related to Outbreaks at the Genomic Scale - Application to RetrospectiveFrontiers in microbiology · 2019Article
- Genetic Separation ofFrontiers in cellular and infection microbiology · 2018Article
- Genetic Stability and Evolution of theApplied and environmental microbiology · 2017Article
- Actin-based motility of bacterial pathogens: mechanistic diversity and its impact on virulence.Pathogens and disease · 2016Article
- Characteristics and distribution of Listeria spp., including Listeria species newly described since 2009.Applied microbiology and biotechnology · 2016Review
- Validation of a Previously Developed Geospatial Model That Predicts the Prevalence of Listeria monocytogenes in New York State Produce Fields.Applied and environmental microbiology · 2016Article
- Novel PCR Assays Complement Laser Biosensor-Based Method and Facilitate Listeria Species Detection from Food.Sensors (Basel, Switzerland) · 2015Article
- Spatial and Temporal Factors Associated with an Increased Prevalence of Listeria monocytogenes in Spinach Fields in New York State.Applied and environmental microbiology · 2015Article
- Comparative Genomics of Listeria Sensu Lato: Genus-Wide Differences in Evolutionary Dynamics and the Progressive Gain of Complex, Potentially Pathogenicity-Related Traits through Lateral Gene Transfer.Genome biology and evolution · 2015Article
- Atypical Listeria innocua strains possess an intact LIPI-3.BMC microbiology · 2014Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genus Listeria includes (i) the opportunistic pathogens L. monocytogenes and L. ivanovii, (ii) the saprotrophs L. innocua, L. marthii, and L. welshimeri, and (iii) L. seeligeri, an apparent saprotroph that nevertheless typically contains the prfA virulence gene cluster. A novel 10-loci multilocus sequence typing scheme was developed and used to characterize 67 isolates representing six Listeria spp. (excluding L. grayi) in order to (i) provide an improved understanding of the phylogeny and evolution of the genus Listeria and (ii) use Listeria as a model to study the evolution of pathogenicity in opportunistic environmental pathogens. Phylogenetic analyses identified six well-supported Listeria species that group into two main subdivisions, with each subdivision containing strains with and without the prfA virulence gene cluster. Stochastic character mapping and phylogenetic analysis of hly, a gene in the prfA cluster, suggest that the common ancestor of the genus Listeria contained the prfA virulence gene cluster and that this cluster was lost at least five times during the evolution of Listeria, yielding multiple distinct saprotrophic clades. L. welshimeri, which appears to represent the most ancient clade that arose from an ancestor with a prfA cluster deletion, shows a considerably lower average sequence divergence than other Listeria species, suggesting a population bottleneck and a putatively different ecology than other saprotrophic Listeria species. Overall, our data suggest that, for some pathogens, loss of virulence genes may represent a selective advantage, possibly by facilitating adaptation to a specific ecological niche.
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