ReviewActa tropica2011
Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos.
Review in Acta tropica, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
162 citing papers in PubMed, 2 syntheses or guidelines pooled it, 352 citations in OpenAlex.
- Thinking beyond Opisthorchis viverrini for risk of cholangiocarcinoma in the lower Mekong region: a systematic review and meta-analysis.Infectious diseases of poverty · 2018Pooled it
- Risk Factors for Cholangiocarcinoma in Thailand: A Systematic Review and Meta-AnalysisAsian Pacific journal of cancer prevention : APJCP · 2018Pooled it
- Pooled Population Pharmacokinetic Analysis of Tribendimidine for the Treatment ofAntimicrobial agents and chemotherapy · 2019Trial
- Serum β-hCG Combined with Traditional Tumor Markers Improves Detection Efficacy and Prognostic Prediction in Cholangiocarcinoma.International journal of molecular sciences · 2026Article
- Spatial prediction of the probability of liver fluke infection using a geographic weighted regression (GWR) model in waterways connecting the Mekong River, Sakon Nakhon of Thailand.One health (Amsterdam, Netherlands) · 2026Article
- Impact of Community-Based Health Education and Sanitation Interventions onInternational journal of environmental research and public health · 2026Article
- How to efficiently establish animal models of cholangiocarcinoma: challenges and inspiration.Medical review (2021) · 2026Review
- Development of a Specific Primer-Based Method for Detecting Bithynia siamensis siamensis, an Intermediate Host of the Liver Fluke Opisthorchis viverrini.Acta parasitologica · 2026Article
- A Proteomics and Metabolomics-based Approach to Biomarkers Identification for the Early Diagnosis of Cholangiocarcinoma in a Hamster Model: A Preliminary Study.Asian Pacific journal of cancer prevention : APJCP · 2026Article
- Consumption of raw or undercooked freshwater fish and awareness of risks of associated bacterial and parasitic infections in Southeast Asia: an online multicountry cross-sectional survey.BMJ public health · 2026Article
- Article
- Silencing serine/arginine-rich splicing factor 1 to induce apoptosis and autophagy-dependent cell death in cholangiocarcinoma through the correction of oncogenic splicing errors.Anatomy & cell biology · 2025Article
- Machine learning approach using electrochemical immunosensor data for precise classification of Opisthorchis viverrini infection.Scientific reports · 2025Article
- Tiliacorinine as a Promising Candidate for Cholangiocarcinoma Therapy via Oxidative Stress Molecule Modulation: A Study Integrating Network Pharmacology, Molecular Docking and Molecular Dynamics Simulation.Antioxidants (Basel, Switzerland) · 2025Article
- Current Prevalence of Infection with Opisthorchis viverrini and Intestinal Parasites in Rural Communities in Northeast Thailand Using Stool Examinations and Serological Screening Methods.The American journal of tropical medicine and hygiene · 2025Article
- Knowledge gaps and risk behaviors among cat owners inOpen veterinary journal · 2025Article
- Ecological epidemiology insights into clonorchiosis endemicity in Guangxi, China and Vietnam: a comprehensive machine learning analysis.International journal of health geographics · 2025Article
- Article
- Effects ofJournal of parasitology research · 2025Article
- The cancer microbiome.Advances in clinical chemistry · 2025Review
102 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 3 countries.
Funding
Abstract
Liver fluke infection caused by Opisthorchis viverrini is a major public health problem in Thailand and the Lao People's Democratic Republic (Lao PDR; Laos). Currently, more than 600 million people are at risk of infection with these fish-borne trematodes and/or their close relatives. Opisthorchiasis has been studied extensively in Thailand, where about 8 million people are infected with the liver fluke. Here we review the pathogenesis, control and re-emergence of O. viverrini infection, in particular in Thailand and, to a lesser extent in Lao PDR given the contiguous geographical range of O. viverrini through these two regions. We also review the association of O. viverrini infection and cholangiocarcinoma, bile duct cancer, and highlight new findings on pathogenesis of liver fluke-induced cholangiocarcinogenesis. Last, we comment on national control strategies in Thailand for the control of O. viverrini infection aimed at reduction in the prevalence of O. viverrini-associated liver cancer in the longer term.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.