ArticleMolecular pain2010
Roles of the anterior cingulate cortex and medial thalamus in short-term and long-term aversive information processing.
Article in Molecular pain, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Brain regions with gestational age differences mediate cognition in adolescents born very premature.Communications biology · 2026Article
- Deep Brain Stimulation, Stereotactic Radiosurgery and High-Intensity Focused Ultrasound Targeting the Limbic Pain Matrix: A Comprehensive Review.Pain and therapy · 2022Review
- The increased in vivo firing of pyramidal cells but not interneurons in the anterior cingulate cortex after neuropathic pain.Molecular brain · 2022Article
- Modulatory effects of photobiomodulation in the anterior cingulate cortex of diabetic rats.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2021Article
- Resting-State Functional Connectivity of the Punishment Network Associated With Conformity.Frontiers in behavioral neuroscience · 2020Article
- Alterations in Regional Homogeneity Assessed by fMRI in Patients with Migraine Without Aura.Journal of medical systems · 2019Article
- Article
- Differential Effects of Inactivation of Discrete Regions of Medial Prefrontal Cortex on Memory Consolidation of Moderate and Intense Inhibitory Avoidance Training.Frontiers in pharmacology · 2017Article
- Electroresponsive properties of rat central medial thalamic neurons.Journal of neurophysiology · 2016Article
- Spatial and temporal plasticity of synaptic organization in anterior cingulate cortex following peripheral inflammatory pain: multi-electrode array recordings in rats.Neuroscience bulletin · 2014Article
- Atypical resting-state functional connectivity of affective pain regions in chronic migraine.Headache · 2013Article
- Ensemble encoding of nociceptive stimulus intensity in the rat medial and lateral pain systems.Molecular pain · 2011Article
- Induction and requirement of gene expression in the anterior cingulate cortex and medial prefrontal cortex for the consolidation of inhibitory avoidance memory.Molecular brain · 2011Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe anterior cingulate cortex (ACC) and medial thalamus (MT) are two of the main components of the medial pain pathway that subserve the affective aspect of pain. The hypothesis of the present study was that the ACC is involved in short-term aversive information processing and that the MT is critical for encoding unconditioned nociceptive information. The roles of these two components in short-term and long-term aversive information processing was investigated using a step-through inhibitory avoidance task.
resultsBehavioral training began 1 week after surgery, in which radiofrequency lesions of the ACC or MT were performed. The retention tests were conducted 30 s (short-term) or 24 h (long-term) after training. Pretraining radiofrequency lesions of the ACC impaired performance in the 30 s, but not 24 h, retention test. Microinfusions of lidocaine into the ACC immediately after training impaired performance in the retention test conducted 10 min later. Pretraining radiofrequency lesions of the MT impaired performance in both the 30 s and 24 h retention tests. However, posttraining, but not pretest, microinfusions of lidocaine into the MT impaired performance in the 24 h retention test.
conclusionsThese results suggest that the ACC may play an important role in short-term, but not long-term, nociceptive information processing. In contrast, the MT may be important for the consolidation of nociceptive information storage.
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