ArticleChronobiology international2010
Altered body mass regulation in male mPeriod mutant mice on high-fat diet.
Article in Chronobiology international, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05413486 (Circadian Disturbances in People With Mental Disease), which is not on this map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Circadian Disturbances in People With Mental Disease
Who cites it
39 citing papers in PubMed.
- Histone methylation: at the crossroad between circadian rhythms in transcription and metabolism.Frontiers in genetics · 2024Review
- The effect of voluntary exercise on light cycle stress-induced metabolic resistance.Physical activity and nutrition · 2023Article
- Effect of early vs. late time-restricted high-fat feeding on circadian metabolism and weight loss in obese mice.Cellular and molecular life sciences : CMLS · 2023Article
- Circadian mechanisms in adipose tissue bioenergetics and plasticity.Genes & development · 2023Review
- Sleep and circadian rhythm disturbance in kidney stone disease: a narrative review.Frontiers in endocrinology · 2023Review
- Mammalian PERIOD2 regulates H2A.Z incorporation in chromatin to orchestrate circadian negative feedback.Nature structural & molecular biology · 2022Article
- Gut microbiota dysbiosis of type 2 diabetic mice impairs the intestinal daily rhythms of GLP-1 sensitivity.Acta diabetologica · 2022Article
- Potential Effect of the Circadian Clock on Erectile Dysfunction.Aging and disease · 2022Article
- Circadian rhythms and pancreas physiology: A review.Frontiers in endocrinology · 2022Review
- Period circadian clock 3 inhibits palmitic acid-induced oxidative stress and inflammatory factor secretion in podocytes.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021Article
- Interconnections between circadian clocks and metabolism.The Journal of clinical investigation · 2021Review
- hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.Cell death & disease · 2021Article
- Metabolic implications of circadian disruption.Pflugers Archiv : European journal of physiology · 2020Review
- A Topological Cluster of Differentially Regulated Genes in Mice Lacking PER3.Frontiers in molecular neuroscience · 2020Article
- Macromolecular Assemblies of the Mammalian Circadian Clock.Molecular cell · 2017Article
- Metabolic disturbances: role of the circadian timing system and sleep.Diabetology international · 2017Article
- Rodent Models for the Analysis of Tissue Clock Function in Metabolic Rhythms Research.Frontiers in endocrinology · 2017Review
- Article
- Review
- Adipose Clocks: Burning the Midnight Oil.Journal of biological rhythms · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The circadian clock orchestrates most physiological processes in mammals. Disruption of circadian rhythms appears to contribute to the development of obesity and metabolic syndrome. The Period genes mPer1 and mPer2, but not mPer3, are essential for core clock function in mice. To assess the impact of mPer genes on body mass regulation, mPer mutant and control mice were fed a high-fat diet. Here the authors report that male mPer1/2/3 triple-deficient mice gain significantly more body mass than wild-type controls on high-fat diet. Surprisingly, mPer3 single-deficient animals mimicked this phenotype, suggesting a previously unrecognized role for mPer3 in body mass regulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.