ArticleWorld journal of gastroenterology2010
Correlation between pre-miR-146a C/G polymorphism and gastric cancer risk in Chinese population.
Article in World journal of gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 14 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 14 syntheses or guidelines pooled it.
- Association between miR-146a rs2910164 polymorphism and specific cancer susceptibility: an updated meta-analysis.Familial cancer · 2018Pooled it
- Pooled it
- A risk of digestive tract neoplasms susceptibility in miR-146a and miR-196a2.Familial cancer · 2015Pooled it
- MiR-146a rs2910164 polymorphism increases risk of gastric cancer: a meta-analysis.World journal of gastroenterology · 2014Pooled it
- MiR-146a rs2910164 G/C polymorphism and gastric cancer susceptibility: a meta-analysis.BMC medical genetics · 2014Pooled it
- miRNA polymorphisms and risk of gastric cancer in Asian population.World journal of gastroenterology · 2014Pooled it
- Effects of common polymorphisms rs2910164 in miR-146a and rs3746444 in miR-499 on cancer susceptibility: a meta-analysis.Molecular biology reports · 2013Pooled it
- The association between two microRNA variants (miR-499, miR-149) and gastrointestinal cancer risk: a meta-analysis.PloS one · 2013Pooled it
- Association between microRNA polymorphisms and cancer risk based on the findings of 66 case-control studies.PloS one · 2013Pooled it
- Different effects of three polymorphisms in MicroRNAs on cancer risk in Asian population: evidence from published literatures.PloS one · 2013Pooled it
- Has-miR-146a polymorphism (rs2910164) and cancer risk: a meta-analysis of 19 case-control studies.Molecular biology reports · 2012Pooled it
- Comprehensive review of genetic association studies and meta-analyses on miRNA polymorphisms and cancer risk.PloS one · 2012Pooled it
- Lack of association of miR-146a rs2910164 polymorphism with gastrointestinal cancers: evidence from 10206 subjects.PloS one · 2012Pooled it
- Increased risk of breast cancer associated with CC genotype of Has-miR-146a Rs2910164 polymorphism in Europeans.PloS one · 2012Pooled it
- Relationship of MicroRNA-146a rs2910164 SNP and tobacco consumption with the susceptibility of digestive system cancer.Discover oncology · 2026Article
- Associations of Single Nucleotide Polymorphism in miR-146a Gene with Susceptibility to Breast Cancer in the Iranian Female.Asian Pacific journal of cancer prevention : APJCP · 2020Article
- Impacts of single nucleotide polymorphisms in three microRNAs (miR-146a, miR-196a2 and miR-499) on the susceptibility to cervical cancer among Indian women.Bioscience reports · 2019Article
- Association between Microrna 146a and Microrna 196a2 Genes Polymorphism and Breast Cancer Risk in North Indian WomenAsian Pacific journal of cancer prevention : APJCP · 2017Article
- MicroRNA gene polymorphisms and the risk of colorectal cancer.Oncology letters · 2017Article
- MiR-146a polymorphism correlates with lung cancer risk in Chinese nonsmoking females.Oncotarget · 2017Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the association between pre-miR-146a C/G polymorphism and gastric cancer risk.
methodsWe performed a hospital-based, case-control study using polymerase chain reaction-restriction fragment length polymorphism method in 608 individuals (304 gastric cancer patients and 304 age and sex matched cancer-free controls).
resultsThe frequencies of pre-miR-146a C/G genotypes in the case group were significantly different from those in the control groups (P = 0.037). Compared with CC genotype carriers, subjects with the variant genotypes (GC + GG) had a 58% increased risk of gastric cancer (adjusted OR = 1.58, 95% CI: 1.11-2.20, P = 0.009). Moreover, a higher gastric cancer risk was especially evident in younger individuals aged < or =58 years, nonsmokers, and males (adjusted OR = 1.76, 95% CI: 1.08-2.87, P = 0.024; adjusted OR = 1.55, 95% CI: 1.06-2.28, P = 0.025; adjusted OR = 1.53, 95% CI: 1.04-2.27, P = 0.033; respectively).
conclusionPre-miR-146a C/G polymorphism might be associated with an elevated risk of gastric cancer in Chinese population.
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