Evidence map›Paper›PMID 20652742›Full record

Trial reportDigestive diseases and sciences2011

The use of a patency capsule in pediatric Crohn's disease: a prospective evaluation.

Stanley A Cohen, Ian M Gralnek, Hagit Ephrath, Angela Stallworth, Tamara Wakhisi

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Digestive diseases and sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Age Is a Risk Factor for Gastroscopy-Assisted Capsule Endoscopy in Children.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024
    Article
  4. Article
  5. Capsule Endoscopy in Children.Frontiers in pediatrics · 2021
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Contraindications for video capsule endoscopy.World journal of gastroenterology · 2016
    Review
  11. Article
  12. Capsule endoscopy in pediatrics: a 10-years journey.World journal of gastroenterology · 2014
    Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stanley A CohenChildren's Center for Digestive Health Care, Children's Healthcare of Atlanta, 993-D Johnson Ferry Road, Suite 440, Atlanta, GA 30342, USA. scohen@ccdhc.org
Ian M Gralnek
Hagit Ephrath
Angela Stallworth
Tamara Wakhisi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCapsule endoscopy (CE) retention remains a concern in patients with suspected or known Crohn's Disease (CD).

aimThe aim of this study was to evaluate the ability of a patency capsule (PC) to establish functional patency in pediatric patients with suspected or known, symptomatic IBD.

methodsA prospective, single center study evaluating the impact of CE on CD management used PC to qualify patients for CE. Patients excreting an intact PC, usually within 40 h of ingestion, were able to undergo standard video CE. Excretion time, structural integrity and patient safety were evaluated.

resultsEighteen patients (10-16 years of age; 9 male; 5 known CD, 3 indeterminate colitis, 1 ulcerative colitis, 9 suspected CD) ingested the PC. Fifteen patients excreted intact PC (mean 34.5 h), 12 patients within 40 h (range 9-60 h). Sixteen (89%) underwent subsequent CE successfully. CD was eventually diagnosed in all patients having PC transit ≥40 h, whereas CD was the diagnosis in 9/12 (75%) in those patients who passed the PC within 40 h. The mean time of passage for an intact PC was 34.7 h, the longest 60 h. There were no capsule retentions or adverse events.

conclusionsThe PC appears to be a useful screening tool for functional patency of the small bowel in suspected or known pediatric CD. Delayed passage of an intact PC requires careful interpretation.

Indexed as

AdolescentCapsule EndoscopesCapsule EndoscopyChildColitis, UlcerativeCrohn DiseaseFemaleHumansMaleMass ScreeningProspective Studies

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.