Evidence map›Paper›PMID 20652603›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2011

Use of unnecessary medications by patients with advanced cancer: cross-sectional survey.

Angelo Fede, Michele Miranda, Daniella Antonangelo, Ligia Trevizan, Henrique Schaffhausser, Bruno Hamermesz, Camile Zimmermann, Auro Del Giglio, Rachel P Riechelmann

Abstract read
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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Potentially inappropriate end-of-life care and its association with relatives' well-being: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  2. Deprescribing in palliative patients with cancer: a concise review of tools and guidelines.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
  3. Reducing potentially inappropriate medications in palliative cancer patients: evidence to support deprescribing approaches.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2014
    Pooled it
  4. Trial
  5. Trial
  6. Deprescribing for patients nearing end of life: views, barriers and facilitators of palliative care patients, carers and nurses.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  13. Review
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  15. The impact of palliative care consults on deprescribing in palliative cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
  16. Observational
  17. Article
  18. Nurses' Perspectives on Family Caregiver Medication Management Support and Deprescribing.Journal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association · 2019
    Article
  19. Deprescribing in palliative care.Clinical medicine (London, England) · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Angelo FedeDepartment of Medical Oncology and Hematology, ABC School of Medicine, Sao Paulo, Brazil.
Michele Miranda
Daniella Antonangelo
Ligia Trevizan
Henrique Schaffhausser
Bruno Hamermesz
Camile Zimmermann
Auro Del Giglio
Rachel P Riechelmann

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer patients at the end of life take numerous medications. However, it has not been assessed what proportion of patients take unnecessary medications and which patients are at risk for doing so.

methodsCross-sectional survey of medications utilized by terminally ill ambulatory cancer patients, with the aim of identifying medications considered unnecessary as per explicit criteria. The criteria took into account whether drugs could benefit patients with terminal cancer.

resultsAmong 87 patients, 21 (24%, 95% confidence interval [CI] 15.6-34.5%) were taking at least one unnecessary medication, the most common being gastric protectors. In multivariable analyses, patients with Charlson Comobidity Index≤1 (OR: 4.49, CI95% 1.32-15.26; p=0.01) or whose medication list had not been reconciled by physicians (OR: 6.38, CI95% 1.21-33.40; p=0.02) were more likely to use an unnecessary medication.

conclusionPatients with advanced cancer take many medications considered unnecessary. Medication reconciliation should be performed routinely for these patients.

Indexed as

AdultAgedAged, 80 and overComorbidityCross-Sectional StudiesFemaleHumansMaleMedication ReconciliationMiddle AgedMultivariate AnalysisNeoplasmsPractice Patterns, Physicians'Retrospective StudiesTerminal CareTerminally Ill

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.