ArticleNanoscale research letters2009
A Quick and Parallel Analytical Method Based on Quantum Dots Labeling for ToRCH-Related Antibodies.
Article in Nanoscale research letters, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Quantum Dot Bioconjugates Enable Order(s)-of-Magnitude Enhancement of Immunoglobulin E Detection Sensitivity.ACS omega · 2026Article
- Micro/nanotechnology-inspired rapid diagnosis of respiratory infectious diseases.Biomedical engineering letters · 2021Review
- Affinity biosensors developed with quantum dots in microfluidic systems.Emergent materials · 2021Review
- A photoelectrochemical sandwich immunoassay for protein S100β, a biomarker for Alzheimer's disease, using an ITO electrode modified with a reduced graphene oxide-gold conjugate and CdS-labeled secondary antibody.Mikrochimica acta · 2019Article
- Nanomedicine advances in toxoplasmosis: diagnostic, treatment, and vaccine applications.Parasitology research · 2017Review
- Simultaneous Quantitative Detection of Helicobacter Pylori Based on a Rapid and Sensitive Testing Platform using Quantum Dots-Labeled Immunochromatiographic Test Strips.Nanoscale research letters · 2016Article
- Capillary-driven surface-enhanced Raman scattering (SERS)-based microfluidic chip for abrin detection.Nanoscale research letters · 2014Article
- A CCD-based reader combined with CdS quantum dot-labeled lateral flow strips for ultrasensitive quantitative detection of CagA.Nanoscale research letters · 2014Article
- Preparation and optimization of matrix metalloproteinase-1-loaded poly(lactide-co-glycolide-co-caprolactone) nanoparticles with rotatable central composite design and response surface methodology.Nanoscale research letters · 2012Article
- Molecular and nanotechnologic approaches to etiologic diagnosis of infectious syndromes.Molecular diagnosis & therapy · 2011Review
- A novel quantum dots-based point of care test for syphilis.Nanoscale research letters · 2010Article
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8 authors.
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Abstract
Quantum dot is a special kind of nanomaterial composed of periodic groups of II-VI, III-V or IV-VI materials. Their high quantum yield, broad absorption with narrow photoluminescence spectra and high resistance to photobleaching, make them become a promising labeling substance in biological analysis. Here, we report a quick and parallel analytical method based on quantum dots for ToRCH-related antibodies including Toxoplasma gondii, Rubella virus, Cytomegalovirus and Herpes simplex virus type 1 (HSV1) and 2 (HSV2). Firstly, we fabricated the microarrays with the five kinds of ToRCH-related antigens and used CdTe quantum dots to label secondary antibody and then analyzed 100 specimens of randomly selected clinical sera from obstetric outpatients. The currently prevalent enzyme-linked immunosorbent assay (ELISA) kits were considered as "golden standard" for comparison. The results show that the quantum dots labeling-based ToRCH microarrays have comparable sensitivity and specificity with ELISA. Besides, the microarrays hold distinct advantages over ELISA test format in detection time, cost, operation and signal stability. Validated by the clinical assay, our quantum dots-based ToRCH microarrays have great potential in the detection of ToRCH-related pathogens.
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