ReviewMediators of inflammation2010
Adipocytokines in atherothrombosis: focus on platelets and vascular smooth muscle cells.
Review in Mediators of inflammation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 71 citations in OpenAlex.
- Trial
- PCSK9 Expression in Vascular Smooth Muscle Cells: Role of Insulin Resistance and High Glucose.International journal of molecular sciences · 2025Article
- Effect of Green Tea Supplementation on Inflammatory Markers among Patients with Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis.Preventive nutrition and food science · 2024Review
- Serum leptin levels in patients with chronic kidney disease and hypertensive heart disease: An observational cross-sectional study.Health science reports · 2023Article
- Dimethylamine enhances platelet hyperactivity in chronic kidney disease model.Journal of bioenergetics and biomembranes · 2021Article
- Influence of Cardiometabolic Risk Factors on Platelet Function.International journal of molecular sciences · 2020Review
- Adipokines: New Potential Therapeutic Target for Obesity and Metabolic, Rheumatic, and Cardiovascular Diseases.Frontiers in physiology · 2020Review
- Relation between platelet coagulant and vascular function, sex-specific analysis in adult survivors of childhood cancer compared to a population-based sample.Scientific reports · 2019Article
- Racial differences in intracerebral haemorrhage outcomes in patients with obesity.Obesity science & practice · 2018Article
- Clinical Significance of Serum IL-6 and TNF-α Levels in Patients with Metabolic Syndrome.Reports of biochemistry & molecular biology · 2017Article
- AdipoRon, an adiponectin receptor agonist, attenuates PDGF-induced VSMC proliferation through inhibition of mTOR signaling independent of AMPK: Implications toward suppression of neointimal hyperplasia.Pharmacological research · 2017Article
- Effect of Bariatric Surgery-Induced Weight Loss on Platelet Count and Mean Platelet Volume: a 12-Month Follow-Up Study.Obesity surgery · 2017Article
- Plasma markers of inflammation and hemostatic and endothelial activity in naturally overweight and obese dogs.BMC veterinary research · 2017Article
- Atorvastatin antagonizes the visfatin-induced expression of inflammatory mediators via the upregulation of NF-κB activation in HCAECs.Oncology letters · 2016Article
- Adipo/cytokines in atherosclerotic secretomes: increased visfatin levels in unstable carotid plaque.BMC cardiovascular disorders · 2016Article
- The cardiovascular impact of visfatin - an inflammation predictor biomarker in metabolic syndrome.Clujul medical (1957) · 2016Review
- Interleukin-1 and acute brain injury.Frontiers in cellular neuroscience · 2015Review
- The Intricate Network of Adipokines and Stroke.International journal of endocrinology · 2015Review
- Reduced vasodilator function following acute resistance exercise in obese women.Frontiers in physiology · 2014Article
- Network analysis of inflammatory genes and their transcriptional regulators in coronary artery disease.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Visceral obesity is a relevant pathological condition closely associated with high risk of atherosclerotic vascular disease including myocardial infarction and stroke. The increased vascular risk is related also to peculiar dysfunction in the endocrine activity of adipose tissue responsible of vascular impairment (including endothelial dysfunction), prothrombotic tendency, and low-grade chronic inflammation. In particular, increased synthesis and release of different cytokines, including interleukins and tumor necrosis factor-alpha (TNF-alpha), and adipokines-such as leptin-have been reported as associated with future cardiovascular events. Since vascular cell dysfunction plays a major role in the atherothrombotic complications in central obesity, this paper aims at focusing, in particular, on the relationship between platelets and vascular smooth muscle cells, and the impaired secretory pattern of adipose tissue.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.