ArticleNature materials2010
Quantum-dot/dopamine bioconjugates function as redox coupled assemblies for in vitro and intracellular pH sensing.
Article in Nature materials, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
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Who cites it
74 citing papers in PubMed, 467 citations in OpenAlex.
- Nickel-Based Nanoparticles Synthesized by Pulsed Laser Ablation in Liquid with Multiphase Structure for Electrochemical Dopamine Sensing.ACS omega · 2026Article
- Cytocompatible FRET Assembly of CdTe@GSH Quantum Dots and Au@BSA Nanoclusters: A Novel Ratiometric Strategy for Dopamine Detection.Molecules (Basel, Switzerland) · 2025Article
- Cytotransducers for Visualization of Spatiotemporal Intercellular Communication.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Bandgap-engineered proteinic near-infrared nanodots for localized precision cancer theranostics.Journal of nanobiotechnology · 2025Article
- Cascade-heterogated proton nanotransistors for multiplex pH-interval imaging.Nature communications · 2025Article
- Phenolic-enabled nanotechnology: a new strategy for central nervous system disease therapy.Journal of Zhejiang University. Science. B · 2024Review
- Micro- and Nanomanufacturing for Biomedical Applications and Nanomedicine: A Perspective.Small science · 2023Article
- Polydopamine-Based Nanoprobes Application in Optical Biosensing.Biosensors · 2023Review
- Nanoparticles for Interrogation of Cell Signaling.Annual review of analytical chemistry (Palo Alto, Calif.) · 2023Review
- Gold nanoparticles-decorated peptide hydrogel for antifouling electrochemical dopamine determination.Mikrochimica acta · 2023Article
- A Dual-network Nerve Adhesive with Enhanced Adhesion Strength Promotes Transected Peripheral Nerve Repair.Advanced functional materials · 2023Article
- Highly sensitive and selective detection of dopamine with boron and sulfur co-doped graphene quantum dots.Scientific reports · 2022Article
- Ratiometric intracellular pH sensors based on nitrogen-doped graphene oxide quantum dots.Heliyon · 2022Article
- The Photophysics and Photochemistry of Melanin- Like Nanomaterials Depend on Morphology and Structure.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Review
- Excitation-emission fluorescence matrix acquired from glutathione capped CdSeS/ZnS quantum dots in combination with chemometric tools for pattern-based sensing of neurotransmitters.Mikrochimica acta · 2021Article
- Smartphone-integrated colorimetric sensor array-based reader system and fluorometric detection of dopamine in male and female geriatric plasma by bluish-green fluorescent carbon quantum dots.Materials today. Bio · 2021Article
- Bioelectronic control of a microbial community using surface-assembled electrogenetic cells to route signals.Nature nanotechnology · 2021Article
- Phenolic-enabled nanotechnology: versatile particle engineering for biomedicine.Chemical Society reviews · 2021Review
- Imaging in vivo acetylcholine release in the peripheral nervous system with a fluorescent nanosensor.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Water-stable perovskite-on-polymer fluorescent microspheres for simultaneous monitoring of pH, urea, and urease.Analytical and bioanalytical chemistry · 2021Article
14 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of semiconductor quantum dots (QDs) for bioimaging and sensing has progressively matured over the past decade. QDs are highly sensitive to charge-transfer processes, which can alter their optical properties. Here, we demonstrate that QD-dopamine-peptide bioconjugates can function as charge-transfer coupled pH sensors. Dopamine is normally characterized by two intrinsic redox properties: a Nernstian dependence of formal potential on pH and oxidation of hydroquinone to quinone by O(2) at basic pH. We show that the latter quinone can function as an electron acceptor quenching QD photoluminescence in a manner that depends directly on pH. We characterize the pH-dependent QD quenching using both electrochemistry and spectroscopy. QD-dopamine conjugates were also used as pH sensors that measured changes in cytoplasmic pH as cells underwent drug-induced alkalosis. A detailed mechanism describing the QD quenching processes that is consistent with dopamine's inherent redox chemistry is presented.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.