Evidence map›Paper›PMID 20651747›Full record

ReviewNature reviews. Immunology2010

The changing face of rheumatoid arthritis: sustained remission for all?

John D Isaacs

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 82 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Cell-based therapies for the treatment of rheumatoid arthritis.Immunity, inflammation and disease · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. PtpA and PknG Proteins Secreted byJournal of inflammation research · 2019
    Article
  15. Review
  16. Calreticulin inhibits inflammation-induced osteoclastogenesis and bone resorption.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2017
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

John D IsaacsInstitute of Cellular Medicine, Musculoskeletal Research Group, Newcastle University Medical School, Framlington Place, Newcastle-upon-Tyne NE2 4HH, UK. j.d.isaacs@ncl.ac.uk
Newcastle University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Earlier diagnosis and treatment, plus biological therapies, have transformed the outlook for many patients with rheumatoid arthritis. In the future, new biomarkers for diagnosis, prognosis and therapeutic response will further improve outcomes. Additionally, preclinical diagnosis and tolerogenic therapies could provide sustained remission for some individuals, although ethical and societal challenges must also be addressed before rheumatoid arthritis becomes 'yesterday's disease'.

Indexed as

Antirheumatic AgentsArthritis, RheumatoidBiomarkersEarly DiagnosisHumansPrognosisRemission InductionTreatment OutcomeAntirheumatic AgentsBiomarkers

Identifiers

PMID20651747
OpenAlexW1989336296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.