Evidence map›Paper›PMID 20651270›Full record

ArticleStroke2010

Gender differences in treatment of severe carotid stenosis after transient ischemic attack.

Sharon N Poisson, S Claiborne Johnston, Stephen Sidney, Jeffrey G Klingman, Mai N Nguyen-Huynh

Open access · bronzeAbstract read
In one paragraph

Article in Stroke, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Sex and hypertensive organ damage: stroke.Journal of human hypertension · 2023
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Carotid Artery Stenosis in Women.Texas Heart Institute journal · 2018
    Review
  9. Article
  10. Carotid stenosis in women: time for a reappraisal.Stroke and vascular neurology · 2016
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sharon N PoissonNational Taiwan University Hospital, Taipei, Taiwan. Sharon.Poisson@UCSFmedctr.org
S Claiborne Johnston
Stephen Sidney
Jeffrey G Klingman
Mai N Nguyen-Huynh
Kaiser Permanente · US

Funding

Acute Outcomes &Management of TIA with Carotid DiseaseK23NS049230 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NGUYEN-HUYNH, MAI N · 2005 to 2009
$807k
NINDS NIH HHS K23 NS049230
6 · The paper itself

Abstract

background and purposeGender differences in carotid endarterectomy (CEA) rates after transient ischemic attack are not well studied, although some reports suggest that eligible men are more likely to have CEA than women after stroke.

methodsWe retrospectively identified all patients diagnosed with transient ischemic attack and >or=70% carotid stenosis on ultrasound in 2003 to 2004 from 19 emergency departments. Medical records were abstracted for clinical data; 90-day follow-up events, including stroke, cardiovascular events, or death; CEA within 6 months; and postoperative 30-day outcomes. We assessed gender as a predictor of CEA and its complications adjusting for demographic and clinical variables as well as time to CEA between groups.

resultsOf 299 patients identified, 47% were women. Women were older with higher presenting systolic blood pressure and less likely to smoke or to have coronary artery disease or diabetes. Fewer women (36.4%) had CEA than men (53.8%; P=0.004). Reasons for withholding surgical treatment were similar in women and men, and there were no differences in follow-up stroke, cardiovascular event, postoperative complications, or death. Time to CEA was also significantly delayed in women.

conclusionsWomen with severe carotid stenosis and recent transient ischemic attack are less likely to undergo CEA than men, and surgeries are more delayed.

Indexed as

Carotid StenosisCohort StudiesEndarterectomy, CarotidFemaleHumansIschemic Attack, TransientMaleRetrospective StudiesSex Factors

Identifiers

PMID20651270
PMCPMC2946224
OpenAlexW2163870846

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.