ArticleAJNR. American journal of neuroradiology2010
Parasellar T2 dark sign on MR imaging in patients with lymphocytic hypophysitis.
Article in AJNR. American journal of neuroradiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Outcomes of Initial Management Strategies in Patients With Autoimmune Lymphocytic Hypophysitis: A Systematic Review and Meta-analysis.The Journal of clinical endocrinology and metabolism · 2022Pooled it
- An update on hypophysitis.Nature reviews. Endocrinology · 2026Review
- Xanthomatous hypophysitis with optic chiasm edema: First documented clinical case.Radiology case reports · 2026Article
- Immune-Mediated Hypophysitis: An Updated Review.Journal of clinical medicine · 2026Review
- The Diagnostic Challenge of Hypophysitis vs. Non-Functioning Pituitary Macroadenomas: An Updated Review and Comparative Analysis of Distinguishing Criteria.Diagnostics (Basel, Switzerland) · 2026Review
- Carotid artery constriction in autoimmune hypophysitis: three case reports and literature review.Endocrine connections · 2025Review
- Comparison of clinical and radiological characteristics of inflammatory and non-inflammatory Rathke cleft cysts.Japanese journal of radiology · 2025Article
- Neuroimaging of hypophysitis: etiologies and imaging mimics.Japanese journal of radiology · 2023Review
- Imaging of pituitary tumors: an update with the 5th WHO Classifications-part 2. Neoplasms other than PitNET and tumor-mimicking lesions.Japanese journal of radiology · 2023Review
- Characteristics of inflammatory and infectious diseases of the pituitary gland in patients undergoing transsphenoidal surgery.Pituitary · 2023Article
- Preoperative differentiation of hypophysitis and pituitary adenomas using a novel clinicoradiologic scoring system.Pituitary · 2022Article
- Erdheim-Chester disease: First pediatric case report in ColombiaBiomedica : revista del Instituto Nacional de Salud · 2021Article
- IgG4-related hypothalamo-hypophysitis.eNeurologicalSci · 2021Article
- Up-To-Date Magnetic Resonance Imaging Findings for the Diagnosis of Hypothalamic and Pituitary Tumors.Yonago acta medica · 2021Review
- MRI Findings of Immune Checkpoint Inhibitor-Induced Hypophysitis: Possible Association with Fibrosis.AJNR. American journal of neuroradiology · 2020Article
- Parasellar T2 dark sign on magnetic resonance imaging to differentiate lymphocytic hypophysitis from pituitary adenoma.Surgical neurology international · 2020Article
- Hypophysitis: An update on the novel forms, diagnosis and management of disorders of pituitary inflammation.Best practice & research. Clinical endocrinology & metabolism · 2019Review
- ISCHEMIC PITUITARY APOPLEXY, HYPOPITUITARISM AND DIABETES INSIPIDUS: A TRIAD UNIQUE TO NECROTIZING HYPOPHYSITIS.Acta clinica Croatica · 2018Article
- Neuro-radiological features can predict hypopituitarism in primary autoimmune hypophysitis.Pituitary · 2018Article
- Pituitary Antibodies in an Adolescent with Secondary Adrenal Insufficiency and Turner Syndrome.Hormone research in paediatrics · 2017Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeMR imaging findings of LYH and pituitary adenomas are similar, but the therapeutic strategies are completely different. The purpose of this study was to evaluate sellar and parasellar MR imaging findings in patients with both diseases, as well as characteristic clinical findings. MATERIALS AND
methodsClinical findings, including endocrinologic study and MR images of 20 patients with LYH and 22 patients with pituitary adenoma, were retrospectively reviewed. We evaluated the MR images in relation to the following: 1) the PPHI on T1-weighted images, 2) thickened stalk (>3.5 mm), 3) pituitary symmetry, 4) pituitary enhancement pattern, 5) a dural tail, and 6) parasellar signal intensity on T2- and T1-weighted images.
resultsBetween patients with LYH and those with pituitary adenoma, a significant difference was identified for the number of patients with loss of PPHI, thickened stalk, pituitary symmetry, homogeneous enhancement, and parasellar dark signal intensity on T2-weighted images by statistical analysis (Fisher exact probability test, P < .05). Among them, only parasellar dark signal intensity on T2-weighted images had no false-positive cases.
conclusionsThe parasellar T2 dark sign can be a specific finding used to distinguish pituitary adenoma from LYH.
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