ArticleBMC infectious diseases2010
Epidemiological and clinical features of rotavirus among children younger than 5 years of age hospitalized with acute gastroenteritis in Northern Italy.
Article in BMC infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 43 citations in OpenAlex.
- Clinical factors predicting rotavirus diarrhea in children: A cross-sectional study from two hospitals.World journal of clinical pediatrics · 2023Article
- Fourteen years' clinical experience and the first million babies protected with human live-attenuated vaccine against rotavirus disease in Italy.Human vaccines & immunotherapeutics · 2021Article
- 10-Year Rotavirus Infection Surveillance: Epidemiological Trends in the Pediatric Population of Perugia Province.International journal of environmental research and public health · 2020Article
- Prevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia.Revista do Instituto de Medicina Tropical de Sao Paulo · 2019Article
- Prevalence and genotypes of group A rotavirus among outpatient children under five years old with diarrhea in Beijing, China, 2011-2016.BMC infectious diseases · 2018Article
- Epidemiological Survey of Rotaviruses Responsible for Infantile Diarrhea by the Immunomolecular Technique in Cotonou (Benin, West Africa).International journal of microbiology · 2018Article
- Detection of Rotavirus in children with acute gastroenteritis in Zagazig University Hospitals in Egypt.Electronic physician · 2015Article
- [Epidemiological and clinical study of rotavirus acute diarrhea in infants at the hospital Jason Sendwe Lubumbashi, Democratic Republic of Congo].The Pan African medical journal · 2015Article
- Review of global rotavirus strain prevalence data from six years post vaccine licensure surveillance: is there evidence of strain selection from vaccine pressure?Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2014Review
- Evidence of VP7 and VP4 intra-lineage diversification in G4P[8] Italian human rotaviruses.Virus genes · 2014Article
- High burden of rotavirus gastroenteritis in young children in rural western Kenya, 2010-2011.The Pediatric infectious disease journal · 2014Article
- Socio-demographic, Clinical and Laboratory Features of Rotavirus Gastroenteritis in Children Treated in Pediatric Clinic.Materia socio-medica · 2013Article
- Burden and typing of rotavirus group a in children with acute gastroenteritis in shiraz, southern iran.Iranian Red Crescent medical journal · 2012Article
- New insights into rotavirus vaccines.Human vaccines & immunotherapeutics · 2012Review
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18 authors at 8 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundRotavirus is the major cause of acute gastroenteritis and severe dehydrating diarrhea in young children.
methodsTo estimate the proportion of hospital admissions for rotavirus acute gastroenteritis and identify the circulating G and P genotypes among children under five years of age, we conducted a prospective observational study from January to December 2008, recruiting children consecutively admitted to six hospitals in Milan and nearby towns in northern Italy. Typing was done on stool samples by reverse transcriptase polymerase chain reaction amplification.
resultsOf the 521 stool samples from children with acute gastroenteritis, 34.9% (95%CI, 30.8 to 39.2%) were rotavirus-positive. Two thirds (67.6%) were under two years of age, and 13.2% were under six months. The predominant G type was G1 (40.7%), followed by G9 (22.5%), G2 (13.2%), G3 (5.5%), G4 (3.8%) and G10 (1.6%). Twenty-one (11.7%) mixed-G infections were identified: G1+G10 (8.8%); G1+G9 (1.6%); and G2+G10 (1.2%). Only P[8] (67.6%) and P[4] (12.6%) types were P genotyped. The predominant single G/P combination was G1P[8] (39.7%), followed by G9P[8] (25.3%), G2P[4] (14.3%), and G3P[8] (4.1%). All G-mixed types combined with P[8].
conclusionsThese findings show an high prevalence of rotavirus infections among children admitted to hospital for acute gastroenteritis caused by different rotavirus strains circulating in the area studied.
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