Evidence map›Paper›PMID 20648701›Full record

ArticlePharmacogenetics and genomics2010

PharmGKB summary: very important pharmacogene information for CYP2B6.

Caroline F Thorn, Jatinder K Lamba, Vishal Lamba, Teri E Klein, Russ B Altman

Abstract read
In one paragraph

Article in Pharmacogenetics and genomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Cytochrome P450 2B6*5 Increases Relapse after Cyclophosphamide-Containing Conditioning and Autologous Transplantation for Lymphoma.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2015
    Trial
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Pharmacogenomics of Opioid Treatment for Pain Management.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  11. Novel associations betweenPharmacogenomics · 2021
    Observational
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Role of Genetic Variations in the Hepatic Handling of Drugs.International journal of molecular sciences · 2020 · on this map
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Caroline F ThornDepartment of Genetics, Stanford University Medical Center, Stanford, California 94305-5120, USA.
Jatinder K Lamba
Vishal Lamba
Teri E Klein
Russ B Altman

Funding

THE STANFORD PHARMACOGENETICS KNOWLEDGE BASEU01GM061374 · NIGMS · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO · 2000 to 2009
$24.0M
NIGMS NIH HHS U01 GM061374NIGMS NIH HHS U01GM61374
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PharmacogeneticsAryl Hydrocarbon HydroxylasesCytochrome P-450 CYP2B6HaplotypesHumansOxidoreductases, N-DemethylatingPolymorphism, Single NucleotideTranscription, GeneticAryl Hydrocarbon HydroxylasesCYP2B6 protein, humanCytochrome P-450 CYP2B6Oxidoreductases, N-Demethylating

Identifiers

PMID20648701
PMCPMC3086041

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.