Evidence map›Paper›PMID 20648234›Full record

ArticleViruses2010

Epidemiologic Observations from Passive and Targeted Surveillance during the First Wave of the 2009 H1N1 Influenza Pandemic in Milwaukee, WI.

Swati Kumar, Michael J Chusid, Rodney E Willoughby, Peter L Havens, Sue C Kehl, Nathan A Ledeboer, Pippa Simpson, Meredith Vandyke, Elizabeth Davis, Kate Gaffney and 3 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Swati KumarMidwest Respiratory Virus Program (MRVP), Suite C450, Pediatric Infectious Diseases, Children's Hospital of Wisconsin, P.O. Box 1997, Milwaukee, WI 53201-1997,USA; mvandyke@mcw.edu (M.V.); edavis@mcw.edu (E.D.); kgaffney@mcw.edu (K.G.); mbose@mcw.edu (M.E.B.); khenrick@mcw.edu (K.J.H.).
Michael J Chusid
Rodney E Willoughby
Peter L Havens
Sue C Kehl
Nathan A Ledeboer
Pippa Simpson
Meredith Vandyke
Elizabeth Davis
Kate Gaffney
Shun-Hwa Li
Michael E Bose
Kelly J Henrickson
Children’s Institute · USChildren's Hospital of Wisconsin · USMedical College of Wisconsin · US

Funding

Rapid point-of-care diagnostic for bioterrorism "A" agents and Pandemic influenzaU01AI070428 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI HENRICKSON, KELLY J. · 2006 to 2010
$8.5M
Diagnostics for Sepsis and Community-Acquired PneumoniaU01AI066584 · NIAID · NEXOGEN, INC. · PI MATHER, PH.D., ELIZABETH L · 2005 to 2009
$2.4M
Multipled POC device for antigen/molecular detection of influenza & other virusesU01AI077988 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI HENRICKSON, KELLY J. · 2008 to 2011
$1.9M
NIAID NIH HHS U01 AI066584NIAID NIH HHS U01 AI070428NIAID NIH HHS U01 AI077988
6 · The paper itself

Abstract

The first wave of the 2009 influenza H1N1 pandemic (H1N1pdm) in Milwaukee, WI has been recognized as the largest reported regional outbreak in the United States. The epidemiologic and clinical characteristics of this large first wave outbreak from April 28(th) 2009-July 25(th) 2009, studied using both passive and targeted surveillance methodologies are presented. A total of 2791 individuals with H1N1pdm infection were identified; 60 % were 5-18 years old. The 5-18 year and 0-4 year age groups had high infection (1131 and 1101 per 100,000) and hospitalization (49 and 12 per 100,000) rates respectively. Non-Hispanic blacks and Hispanics had the highest hospitalization and infection rates. In targeted surveillance, infected patients had fever (78%), cough (80%), sore throat (38%), and vomiting or diarrhea (8%). The "influenza like illness" definition captured only 68 % of infected patients. Modeling estimates that 10.3 % of Milwaukee population was infected in the first wave and 59% were asymptomatic. The distinct epidemiologic profile of H1N1pdm infections observed in the study has direct implications for predicting the burden of infection and hospitalization in the next waves of H1N1pdm. Careful consideration of demographic predictors of infection and hospitalization with H1N1pdm will be important for effective preparedness for subsequent influenza seasons.

Identifiers

PMID20648234
PMCPMC2905828
OpenAlexW2073964145

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.