Evidence map›Paper›PMID 20648233›Full record

ArticleEngineering with computers2009

Nanoshell-mediated laser surgery simulation for prostate cancer treatment.

Yusheng Feng, David Fuentes, Andrea Hawkins, Jon Bass, Marissa Nichole Rylander, Andrew Elliott, Anil Shetty, R Jason Stafford, J Tinsley Oden

Abstract read
In one paragraph

Article in Engineering with computers, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Multiphysics Modeling of Plasmonic Photothermal Heating Effects in Gold Nanoparticles and Nanoparticle Arrays.The journal of physical chemistry. C, Nanomaterials and interfaces · 2020
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  13. Optimization and real-time control for laser treatment of heterogeneous soft tissues.Computer methods in applied mechanics and engineering · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yusheng FengComputational Bioengineering and Nanotechnology Lab, Department of Mechanical Engineering, The University of Texas at San Antonio, San Antonio, TX 78249, USA yusheng.feng@utsa.edu.
David Fuentes
Andrea Hawkins
Jon Bass
Marissa Nichole Rylander
Andrew Elliott
Anil Shetty
R Jason Stafford
J Tinsley Oden

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Jared Kyle Burks · 1985 to 2026
$290.8M
MRTI Guided Integrative Model for Cancer TreatmentK25CA116291 · NCI · UNIVERSITY OF TEXAS SAN ANTONIO · PI FENG, YUSHENG · 2007 to 2011
$694k
NCI NIH HHS K25 CA116291NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

Laser surgery, or laser-induced thermal therapy, is a minimally invasive alternative or adjuvant to surgical resection in treating tumors embedded in vital organs with poorly defined boundaries. Its use, however, is limited due to the lack of precise control of heating and slow rate of thermal diffusion in the tissue. Nanoparticles, such as nanoshells, can act as intense heat absorbers when they are injected into tumors. These nanoshells can enhance thermal energy deposition into target regions to improve the ability for destroying larger cancerous tissue volumes with lower thermal doses. The goal of this paper is to present an integrated computer model using a so-called nested-block optimization algorithm to simulate laser surgery and provide transient temperature field predictions. In particular, this algorithm aims to capture changes in optical and thermal properties due to nanoshell inclusion and tissue property variation during laser surgery. Numerical results show that this model is able to characterize variation of tissue properties for laser surgical procedures and predict transient temperature fields comparable to those measured by in vivo magnetic resonance temperature imaging techniques. Note that the computational approach presented in the study is quite general and can be applied to other types of nanoparticle inclusions.

Identifiers

PMID20648233
PMCPMC2905827

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.