Evidence map›Paper›PMID 20648013›Full record

ArticleBritish journal of cancer2010

Alcohol intake and risk of colorectal cancer: results from the UK Dietary Cohort Consortium.

J Y Park, C C Dahm, R H Keogh, P N Mitrou, B J Cairns, D C Greenwood, E A Spencer, I S Fentiman, M J Shipley, E J Brunner and 10 more

Open access · hybridAbstract read
In one paragraph

Article in British journal of cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 1 country.

J Y ParkDepartment of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.
C C Dahm
R H Keogh
P N Mitrou
B J Cairns
D C Greenwood
E A Spencer
I S Fentiman
M J Shipley
E J Brunner
J E Cade
V J Burley
G D Mishra
D Kuh
A M Stephen
I R White
R N Luben
A A Mulligan
K-T Khaw
S A Rodwell
Medical Research Council · GBUniversity of Cambridge · GBUniversity of Leeds · GBUniversity College London · GBUniversity of Oxford · GBGuy's Hospital · GBMRC Unit for Lifelong Health and Ageing · GB

Funding

British Heart Foundation RG/07/008/23674Cancer Research UKDepartment of HealthMedical Research Council G0100222Medical Research Council G0401527Medical Research Council G0500300Medical Research Council G0902037Medical Research Council G19/35Medical Research Council G8802774Medical Research Council MC_U105260558Medical Research Council MC_U105630924Medical Research Council MC_U105960384Medical Research Council MC_U123092725Medical Research Council MC_U123092726Medical Research Council U.1052.00.006(60558)
6 · The paper itself

Abstract

backgroundEpidemiological studies have suggested that excessive alcohol intake increases colorectal cancer (CRC) risk. However, findings regarding tumour subsites and sex differences have been inconsistent.

methodsWe investigated the prospective associations between alcohol intake on overall and site- and sex-specific CRC risk. Analyses were conducted on 579 CRC cases and 1996 matched controls nested within the UK Dietary Cohort Consortium using standardised data obtained from food diaries as a main nutritional method and repeated using data from food frequency questionnaire (FFQ).

resultsCompared with individuals in the lightest category of drinkers (>0-<5 g per day), the multivariable odds ratios of CRC were 1.16 (95% confidence interval (95% CI): 0.88, 1.53) for non-drinkers, 0.91 (95% CI: 0.67, 1.24) for drinkers with 5-<15 g per day, 0.90 (95% CI: 0.65, 1.25) for drinkers with 15-<30 g per day, 1.02 (95% CI: 0.66, 1.58) for drinkers with 30-<45 g per day and 1.19 (95% CI: 0.75, 1.91) for drinkers with >or=45 g per day. No clear associations were observed between site-specific CRC risk and alcohol intake in either sex. Analyses using FFQ showed similar results.

conclusionWe found no significantly increased risk of CRC up to 30 g per day of alcohol intake within the UK Dietary Cohort Consortium.

Indexed as

Alcohol DrinkingCase-Control StudiesColorectal NeoplasmsDietFemaleHumansMaleMiddle AgedRisk FactorsSmokingUnited Kingdom

Identifiers

PMID20648013
PMCPMC2938250
OpenAlexW2083181004

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.