Evidence map›Paper›PMID 20647790›Full record

ReviewCritical care medicine2010

Recognition and prevention of hospital-associated enteric infections in the intensive care unit.

Linda D Bobo, Erik R Dubberke

Registry-linked trialAbstract readReview
In one paragraph

Review in Critical care medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01552668 (The Effect of a Twice Daily, 200 mg Dose of Oral Fidaxomicin Compared to Placebo on Risk of Acquiring C. Difficile and Developing C. Difficile Infection), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01552668 phase4withdrawnnot on this mapstarted 2012, after this paper: background citation

The Effect of a Twice Daily, 200 mg Dose of Oral Fidaxomicin Compared to Placebo on Risk of Acquiring C. Difficile and Developing C. Difficile Infection (CDI) in High Risk Patients

TypeinterventionalSponsorWashington University School of MedicineRan2012 to 2013Enrolled0ConditionsClostridium Difficile InfectionArmsFidaxomicin, Placebo
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Unravelling the Persistence of the Rare SerovarPathogens (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Guidelines for Antibiotics Prescription in Critically Ill Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  6. Article
  7. Article
  8. Guidelines for Antibiotic Prescription in Intensive Care Unit.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Comparison of five assays for detection of Clostridium difficile toxin.The Journal of molecular diagnostics : JMD · 2011
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Linda D BoboDepartment of Medicine, Washington University School of Medicine, St Louis, MO, USA. lbobo@DOM.wustl.edu
Erik R Dubberke
Washington University in St. Louis · US

Funding

C. DIFFICILE DISEASE IN STEM CELL TRANSPLANT RECIPIENTSK23AI065806 · NIAID · WASHINGTON UNIVERSITY · PI DUBBERKE, ERIK R · 2009 to 2011
$374k
NIAID NIH HHS 1K23AI065806-01A2NIAID NIH HHS K23 AI065806NIAID NIH HHS L30 AI062141
6 · The paper itself

Abstract

The objectives of this article were to review the causes and extent of hospital-associated infectious diarrhea and associated risks in the general hospital ward and intensive care unit (ICU), to compare microorganisms with similar symptoms to aid in recognition that will lead to timely and appropriate treatment and control measures, and to propose infection prevention protocols that could decrease human process errors in the ICU. This literature review describes epidemiology, comparison of microbial characteristics for potential hospital-associated enteric pathogens, diagnosis, and prevention, especially if important in the ICU, and particularly in regard to Clostridium difficile. Enteric organisms that most commonly cause hospital-associated infectious diarrhea in acute care settings and the ICU are C. difficile, rotavirus, and norovirus, although others may also be important, particularly in developing countries. To recognize and control infectious diarrhea successfully in the ICU, intensivists should be aware that epidemiology, risks, and prevention measures may differ between these microorganisms. In addition, intensivists should be ready to implement systems changes related to notification, isolation precautions and prevention, and environmental cleaning in the ICU.

Indexed as

Infection ControlIntensive Care UnitsCaliciviridae InfectionsClostridioides difficileCross InfectionCryptosporidiosisDiarrheaDisinfectionEnterocolitis, PseudomembranousFecesGastroenteritisHand DisinfectionHumansNorovirusPatient IsolationRotavirus Infections

Identifiers

PMID20647790
PMCPMC3657464
OpenAlexW2046917644

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.