ReviewEpigenetics2010
Human non-CG methylation: are human stem cells plant-like?
Review in Epigenetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- The molecular basis for recognition of 5'-NNNCC-3' PAM and its methylation state by Acidothermus cellulolyticus Cas9.Nature communications · 2020Article
- The effects of the neonicotinoid imidacloprid on gene expression and DNA methylation in the buff-tailed bumblebee Bombus terrestris.Proceedings. Biological sciences · 2019Article
- Identification of differential genomic DNA Methylation in the hypothalamus of pubertal rat using reduced representation Bisulfite sequencing.Reproductive biology and endocrinology : RB&E · 2017Article
- Genome-wide DNA methylation reprogramming in response to inorganic arsenic links inhibition of CTCF binding, DNMT expression and cellular transformation.Scientific reports · 2017Article
- Mammalian non-CG methylations are conserved and cell-type specific and may have been involved in the evolution of transposon elements.Scientific reports · 2016Article
- Non-CG Methylation in the Human Genome.Annual review of genomics and human genetics · 2015Review
- Characterizing the strand-specific distribution of non-CpG methylation in human pluripotent cells.Nucleic acids research · 2014Article
- Single-base resolution of mouse offspring brain methylome reveals epigenome modifications caused by gestational folic acid.Epigenetics & chromatin · 2014Article
- Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency.Nature cell biology · 2013Article
- Analysis of promoter non-CG methylation in prostate cancer.Epigenomics · 2013Article
- Article
- Resources for methylome analysis suitable for gene knockout studies of potential epigenome modifiers.GigaScience · 2012Article
- Article
- Eyes on DNA methylation: current evidence for DNA methylation in ocular development and disease.Journal of ocular biology, diseases, and informatics · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Non-CG methylation is well characterized in plants, where it appears to play a role in gene silencing and genomic imprinting. Although strong evidence for the presence of non-CG methylation in animals has been available for some time, both its origin and function remain elusive. In this review we discuss available evidence on non-CG methylation in animals in light of evidence suggesting that the human stem cell methylome contains significant levels of methylation outside the CG site.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.