Insulin, glucose and the increased risk of cancer in patients with type 2 diabetes.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

20 citing papers in PubMed.

1. Diabetes and tumor risk: a 23-year Danish national cohort study.Frontiers in endocrinology · 2025
   Article
2. Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.Cell death & disease · 2021
   Article
3. Metformin Clinical Trial in HPV+ and HPV- Head and Neck Squamous Cell Carcinoma: Impact on Cancer Cell Apoptosis and Immune Infiltrate.Frontiers in oncology · 2018
   Article
4. Diabetes and risk of cancer incidence: results from a population-based cohort study in northern Italy.BMC cancer · 2017
   Article
5. Diabetes-associated dysregulated cytokines and cancer.Integrative cancer science and therapeutics · 2016
   Article
6. Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage.BioMed research international · 2015
   Review
7. Hyperglycemia as a risk factor for cancer progression.Diabetes & metabolism journal · 2014
   Review
8. Diabetes and cancer: two diseases with obesity as a common risk factor.Diabetes, obesity & metabolism · 2014
   Review
9. Lessons from mouse models of high-fat diet-induced NAFLD.International journal of molecular sciences · 2013
   Review
10. Do statins cause diabetes?Current diabetes reports · 2013
    Review
11. Disease-specific mortality and secondary primary cancer in well-differentiated thyroid cancer with type 2 diabetes mellitus.PloS one · 2013
    Article
12. Protection from non-alcoholic steatohepatitis and liver tumourigenesis in high fat-fed insulin receptor substrate-1-knockout mice despite insulin resistance.Diabetologia · 2012
    Article
13. Imbalance of angiogenesis in diabetic complications: the mechanisms.International journal of preventive medicine · 2012
    Article
14. Metformin and its clinical use: new insights for an old drug in clinical practice.Archives of medical science : AMS · 2012
    Article
15. Diabetes and cancer (1): evaluating the temporal relationship between type 2 diabetes and cancer incidence.Diabetologia · 2012
    Review
16. Diabetes, insulin and cancer risk.World journal of diabetes · 2012
    Article
17. Insulin glargine and risk of cancer: a cohort study in the French National Healthcare Insurance Database.Diabetologia · 2012
    Article
18. Impact of glucose tolerance on the severity of non-alcoholic steatohepatitis.Journal of diabetes investigation · 2011
    Article
19. Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells.Cancer biology & therapy · 2011
    Article
20. Metformin and other biguanides in oncology: advancing the research agenda.Cancer prevention research (Philadelphia, Pa.) · 2010
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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