Evidence map›Paper›PMID 20645033›Full record

ReviewCurrent treatment options in oncology2010

Exercise therapy in the management of solid tumors.

Lee W Jones, Jeffrey Peppercom, Jessica M Scott, Claudio Battaglini

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Current treatment options in oncology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01843608 (Effect of Combined Training Post-treatment Intervention in Lean Body Mass Recovery in Breast Cancer Survival. A Randomised Controlled Trial.), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01843608 naunknown statusnot on this mapstarted 2013, after this paper: background citation

Effect of Combined Training Post-treatment Intervention in Lean Body Mass Recovery in Breast Cancer Survival. A Randomised Controlled Trial.

TypeinterventionalSponsorUniversidad Politecnica de MadridRan2013 to 2014Enrolled90ConditionsSarcopenic Obesity in Breast Cancer Survival, Muscle Strength Quantitative Trait Locus 1, Cardiopulmonary Capacity, Quality of LifeArmsPhysical Intervention
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Recreational Running Motivations among Breast Cancer Survivors.International journal of environmental research and public health · 2022
    Article
  4. Article
  5. Review
  6. Validation of 2 Submaximal Cardiorespiratory Fitness Tests in Patients With Breast Cancer Undergoing Chemotherapy.Rehabilitation oncology (American Physical Therapy Association. Oncology Section) · 2016
    Article
  7. Running away from side effects: physical exercise as a complementary intervention for breast cancer patients.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2015
    Review
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Lee W JonesDuke University Medical Center, Box 3085, Durham, NC 27710, USA, lee.w.jones@duke.edu
Jeffrey Peppercom
Jessica M Scott
Claudio Battaglini
Duke Medical Center · USDuke University Hospital · USJohnson Space Center · USUniversity of North Carolina at Chapel Hill · US

Funding

Randomized Trial of Optimal Type of Aerobic Training in Breast CancerR01CA142566 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI JONES, LEE W · 2010 to 2017
$2.7M
Phase III Trial of Exercise Training in Postsurgical Lung CancerR01CA138624 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI JONES, LEE W · 2009 to 2013
$2.1M
Synergistically Acting Targeted Therapeutics for MelanomaR01CA138634 · NCI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI ROBERTSON, GAVIN P. · 2010 to 2014
$1.5M
Phase II Trial of Aerobic Training in Metastatic Breast CancerR21CA143254 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI JONES, LEE W · 2010 to 2012
$536k
Exercise Training, Erectile Dysfunction, and Prostate CancerR21CA133895 · NCI · DUKE UNIVERSITY · PI JONES, LEE W · 2009 to 2011
$503k
Using Message Framing to Promote Physical Activity in Colorectal Cancer SurvivorsR21CA125458 · NCI · DUKE UNIVERSITY · PI JONES, LEE W · 2008 to 2009
$421k
NCI NIH HHS CA125458NCI NIH HHS CA133895NCI NIH HHS CA138634NCI NIH HHS CA142566NCI NIH HHS CA143254NCI NIH HHS R01 CA138624NCI NIH HHS R01 CA138634NCI NIH HHS R01 CA142566NCI NIH HHS R21 CA125458NCI NIH HHS R21 CA133895NCI NIH HHS R21 CA143254
6 · The paper itself

Abstract

OPThe benefits of exercise in patients with chronic disease have been studied extensively over the last half century. In contrast, investigation of the role of exercise following a diagnosis of cancer has received comparably less attention. In this article, we review the efficacy of exercise training in specific areas across the cancer survivorship continuum [i.e., pre-surgery, post-surgery during adjuvant therapy, following the completion of primary adjuvant therapy (survivorship), and palliation], with a view toward future research. The current evidence base provides strong but preliminary evidence that exercise training is a well-tolerated and safe adjunct therapy that can mitigate several common treatment-related side-effects among cancer patients with early disease both during and following adjuvant therapy although many questions remain unanswered. Preliminary evidence in this area supports that exercise therapy may be an important consideration in multidisciplinary management of patients following a cancer diagnosis.

Indexed as

Exercise TherapyHumansNeoplasmsTreatment Outcome

Identifiers

PMID20645033
PMCPMC3619217
OpenAlexW2080715702

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.