ArticleDeutsches Arzteblatt international2010
Body mass index, waist circumference, and the risk of type 2 diabetes mellitus: implications for routine clinical practice.
Article in Deutsches Arzteblatt international, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03711682 (Hypoglycemic Effect of Cinnamomum Verum in Type 2 Diabetic Patients in the Municipality of Comasagua), which is not on this map. Cited by 77 papers, 7 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Hypoglycemic Effect of Cinnamomum Verum in Type 2 Diabetic Patients in the Municipality of Comasagua
Who cites it
77 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- The effect of turmeric/curcumin supplementation on anthropometric indices in subjects with prediabetes and type 2 diabetes mellitus: A GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials.Nutrition & diabetes · 2025Pooled it
- The effects of chicory inulin-type fructans supplementation on weight management outcomes: systematic review, meta-analysis, and meta-regression of randomized controlled trials.The American journal of clinical nutrition · 2024Pooled it
- Incidence and temporal trends in type 2 diabetes by weight status: A systematic review and meta-analysis of prospective cohort studies.Journal of global health · 2023Pooled it
- Association of weight status and the risks of diabetes in adults: a systematic review and meta-analysis of prospective cohort studies.International journal of obesity (2005) · 2022Pooled it
- The Association between Body Composition using Dual energy X-ray Absorptiometry and Type-2 Diabetes: A Systematic Review and Meta-Analysis of Observational studies.Scientific reports · 2019Pooled it
- Changes in Waist Circumference among German Adults over Time - Compiling Results of Seven Prospective Cohort Studies.Obesity facts · 2016Pooled it
- Pleiotropic effects of obesity-susceptibility loci on metabolic traits: a meta-analysis of up to 37,874 individuals.Diabetologia · 2013Pooled it
- Evaluation of Metabolic Syndrome and Its Associated Risk Factors in Type 2 Diabetes: A Descriptive Cross-Sectional Study at the Komfo Anokye Teaching Hospital, Kumasi, Ghana.BioMed research international · 2019Trial
- Association Between Anthropometric Indices and Presence of Type 2 Diabetes Mellitus in Obesity.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026Article
- Abdominal waist circumference and subcutaneous adipose tissue thickness predicts development of post-transplant diabetes mellitus.International urology and nephrology · 2026Article
- Association between trajectories of waist circumference with incidence of type 2 diabetes mellitus, Tehran lipid and glucose study.Scientific reports · 2026Article
- Abdominal Waist Circumference and Subcutaneous Adipose Tissue Thickness Predicts Development of Post-Transplant Diabetes Mellitus.Research square · 2026Article
- Associations of sociodemographic factors and lifestyle behaviors with the risk of cardiometabolic disease: a population-based study from the European health interview survey in Hungary.BMC public health · 2026Article
- Prevalence and factors associated with comorbidities in Iranian patients with type 2 diabetes: A national study.PloS one · 2026Article
- Global patterns of visceral adiposity and cardiometabolic disease.Nature reviews. Endocrinology · 2026Article
- Waist-to-hip ratio better reflect beta-cell function and predicts diabetes risk in adult with overweight or obesity.Annals of medicine · 2025Article
- Examining gender, BMI, and lifestyle factors as indicators of type 2 diabetes risk in the Ukrainian population.Endocrine · 2025Article
- Beyond association: Examining overweight as a mediator in the link between depression and diabetes.World journal of diabetes · 2025Article
- Assessment of periodontitis as a predictive sign of occurrence of type-II diabetes mellitus.The Saudi dental journal · 2025Article
- Article
17 more citing papers are in PubMed but not listed here.
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Abstract
backgroundCurrent guidelines for assessing the risk of developing type 2 diabetes mellitus (DM) recommend using the patient's body-mass index (BMI) as a primary measure. Waist circumference measurement is recommended for overweight or obese patients only (BMI > or = 25).
methodsWe studied the interaction between BMI and waist circumference with respect to the risk of developing type 2 DM in a cohort of 9753 men and 15491 women, aged 35 to 65, who participated in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam. The statistical analysis was performed with multivariable-adjusted Cox proportional hazard regression.
resultsDuring a mean follow-up interval of 8 years, type 2 DM was newly diagnosed in 583 men and 425 women. A statistically significant interaction was found between BMI and waist circumference with respect to the risk of type 2 DM (p<0.0001). The positive association between waist circumference and diabetes risk was stronger in persons with lower BMI. The relative risk (RR) of developing type 2 DM among persons of low or normal weight (BMI < 25) who had a large waist circumference was at least as high as that among overweight persons (BMI 25-29.9) with a small waist circumference: for the first case, the RR was 3.62 [1.67-7.83] in men and 2.74 [1.52-4.94] in women; for the second case, the RR was 2.26 [1.51-3.37] in men and 1.40 [0.61-3.19] in women (The figures in square brackets are 95% confidence intervals). These relative risks were calculated in comparison to the risk among persons of low or normal weight (BMI < 25) with a small waist circumference.
conclusionThese findings imply that the waist circumference is an important additional piece of information for assessing the risk of type 2 DM, particularly among persons of low or normal weight.
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