ReviewJournal of the American Academy of Child and Adolescent Psychiatry2010
Quantitative genetics in the era of molecular genetics: learning abilities and disabilities as an example.
Review in Journal of the American Academy of Child and Adolescent Psychiatry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of attention deficit hyperactivity disorder (ADHD) and mathematical ability: current findings and future implications.BMC medicine · 2015Pooled it
- Genetic specificity of face recognition.Proceedings of the National Academy of Sciences of the United States of America · 2015Trial
- Language difficulties are a shared risk factor for both reading disorder and mathematics disorder.Journal of experimental child psychology · 2021Article
- The Influence of Dyslexia Candidate Genes on Reading Skill in Old Age.Behavior genetics · 2018Article
- Single Nucleotide Polymorphisms Associated with Reading Ability Show Connection to Socio-Economic Outcomes.Behavior genetics · 2017Article
- Expanding the phenotype of Triple X syndrome: A comparison of prenatal versus postnatal diagnosis.American journal of medical genetics. Part A · 2016Article
- Genetic link between family socioeconomic status and children's educational achievement estimated from genome-wide SNPs.Molecular psychiatry · 2016Article
- Stability and Change in Genetic and Environmental Influences on Well-Being in Response to an Intervention.PloS one · 2016Article
- Association between AVPR1A, DRD2, and ASPM and endophenotypes of communication disorders.Psychiatric genetics · 2014Article
- Epigenetic analysis of neurocognitive development at 1 year of age in a community-based pregnancy cohort.Behavior genetics · 2014Article
- DNA evidence for strong genetic stability and increasing heritability of intelligence from age 7 to 12.Molecular psychiatry · 2014Article
- From observational to dynamic genetics.Frontiers in genetics · 2014Article
- The future of genomics for developmentalists.Development and psychopathology · 2013Review
- Common DNA markers can account for more than half of the genetic influence on cognitive abilities.Psychological science · 2013Article
- Twins Early Development Study (TEDS): a genetically sensitive investigation of cognitive and behavioral development from childhood to young adulthood.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2013Article
- Visual analysis of geocoded twin data puts nature and nurture on the map.Molecular psychiatry · 2012Article
- Dopaminergic polymorphisms and educational achievement: results from a longitudinal sample of Americans.Developmental psychology · 2012Article
- The timing of educational investment: a neuroscientific perspective.Developmental cognitive neuroscience · 2012Review
- Word reading fluency: role of genome-wide single-nucleotide polymorphisms in developmental stability and correlations with print exposure.Child developmentArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
objectiveTo consider recent findings from quantitative genetic research in the context of molecular genetic research, especially genome-wide association studies. We focus on findings that go beyond merely estimating heritability. We use learning abilities and disabilities as examples.
methodRecent twin research in the area of learning abilities and disabilities was reviewed.
resultsThree findings from quantitative genetic research stand out for their far-reaching implications for child and adolescent psychiatry. First, common disorders such as learning difficulties are the quantitative extreme of the same genetic factors responsible for genetic influence throughout the normal distribution (the Common Disorders are Quantitative Traits Hypothesis). Second, the same set of genes is largely responsible for genetic influence across diverse learning and cognitive abilities and disabilities (the Generalist Genes Hypothesis). Third, experiences are just as influenced genetically as are behaviors and genetic factors mediate associations between widely used measures of the environment and behavioural outcomes (the Nature of Nurture Hypothesis).
conclusionsQuantitative genetics can go far beyond the rudimentary "how much" question about nature versus nurture, and can continue to provide important findings in the era of molecular genetics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.