Evidence map›Paper›PMID 20643221›Full record

ReviewSeminars in cell & developmental biology2011

New links between vesicle coats and Rab-mediated vesicle targeting.

Cortney G Angers, Alexey J Merz

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 73 citations in OpenAlex.

  1. Piezo1 selectively enhances TGF-β1-induced IgA class switching by B cells.Cellular and molecular life sciences : CMLS · 2025
    Article
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  4. Review
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  10. Neurogenic inflammation and its role in migraine.Seminars in immunopathology · 2018
    Review
  11. Article
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  13. Article
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  15. Article
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  17. The delivery of therapeutic oligonucleotides.Nucleic acids research · 2016
    Review
  18. Review
  19. Coat/Tether Interactions-Exception or Rule?Frontiers in cell and developmental biology · 2016
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Cortney G AngersDepartment of Biochemistry, University of Washington School of Medicine, Seattle, WA 98195-3750, USA.
Alexey J Merz
University of Washington · US

Funding

Dynamics of Endomembrane Docking and FusionR01GM077349 · NIGMS · UNIVERSITY OF WASHINGTON · PI MERZ, ALEXEY JARRELL · 2006 to 2024
$6.1M
NIGMS NIH HHS GM077349NIGMS NIH HHS R01 GM077349
6 · The paper itself

Abstract

Vesicle trafficking is a highly regulated process that transports proteins and other cargoes through eukaryotic cells while maintaining cellular organization and compartmental identity. In order for cargo to reach the correct destination, each step of trafficking must impart specificity. During vesicle formation, this is achieved by coat proteins, which selectively incorporate cargo into the nascent vesicle. Classically, vesicle coats are thought to dissociate shortly after budding. However, recent studies suggest that coat proteins can remain on the vesicle en route to their destination, imparting targeting specificity by physically and functionally interacting with Rab-regulated tethering systems. This review focuses on how interactions among Rab GTPases, tethering factors, SNARE proteins, and vesicle coats contribute to vesicle targeting, fusion, and coat dynamics.

Indexed as

AnimalsBiological TransportCoated VesiclesHumansProtein BindingProtein Subunitsrab GTP-Binding ProteinsProtein Subunitsrab GTP-Binding Proteins

Identifiers

PMID20643221
PMCPMC3196633
OpenAlexW2062237973

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.