Evidence map›Paper›PMID 20643079›Full record

ArticleBiophysical journal2010

Electric field-driven disruption of a native beta-sheet protein conformation and generation of a helix-structure.

Pedro Ojeda-May, Martin E Garcia

Abstract read
In one paragraph

Article in Biophysical journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  5. Review
  6. Article
  7. Aerodynamics and the role of the earth's electric field in the spiders' ballooning flight.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2021
    Review
  8. Electro-opening of a microtubule lattice in silico.Computational and structural biotechnology journal · 2021
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pedro Ojeda-MayTheoretische Physik, Universität Kassel, Fachbereich 10, Kassel, Germany. pojeda@physik.uni-kassel.de
Martin E Garcia

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We demonstrate that an external constant electric field is able to modify the secondary structure of a protein and induce a transition from a beta-sheet into a helix-like conformation. This dramatic change is driven by a global rearrangement of the dipole moments at the amide planes. We also predict electric-field-induced modifications of the intermediate states of the protein.

Indexed as

ElectricityAmidesHIV Envelope Protein gp120Protein Structure, SecondaryThermodynamicsAmidesHIV Envelope Protein gp120

Identifiers

PMID20643079
PMCPMC2905109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.