ArticleScandinavian journal of primary health care2010
Vitamin D status in patients with musculoskeletal pain, fatigue and headache: a cross-sectional descriptive study in a multi-ethnic general practice in Norway.
Article in Scandinavian journal of primary health care, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01263288 (Effect of Vitamin D Supplementation on Muscular Strength, Musculoskeletal Pain and Headache in Immigrants Living in Norway. Randomized, Double Blinded, Placebo Controlled Study), which is not on this map. Cited by 70 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Vitamin D Supplementation on Muscular Strength, Musculoskeletal Pain and Headache in Immigrants Living in Norway. Randomized, Double Blinded, Placebo Controlled Study
Who cites it
70 citing papers in PubMed, 3 syntheses or guidelines pooled it, 147 citations in OpenAlex.
- The Efficacy of Vitamin D Supplementation in the Treatment of Fibromyalgia Syndrome and Chronic Musculoskeletal Pain.Nutrients · 2022Pooled it
- Vitamin D in migraine headache: a comprehensive review on literature.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019Pooled it
- Does vitamin D supplementation alleviate chronic nonspecific musculoskeletal pain? A systematic review and meta-analysis.Clinical rheumatology · 2017Pooled it
- Effects of vitamin D on insulin resistance and fasting blood glucose in pregnant women with insufficient or deficient vitamin D: a randomized, placebo-controlled trial.BMC endocrine disorders · 2022Trial
- Effect of vitamin D3 on self-perceived fatigue: A double-blind randomized placebo-controlled trial.Medicine · 2016Trial
- Effect of vitamin D3 supplementation on iron status: a randomized, double-blind, placebo-controlled trial among ethnic minorities living in Norway.Nutrition journal · 2016Trial
- Vitamin D concentrations and headache risk in children and adolescents aged 6 to 19 years: The mediating role of body mass index.Medicine · 2026Article
- Prescribing trends and clinical impact of calcium salt supplements in musculoskeletal pain: evidence from a multi-center retrospective analysis in India (TRACE study).BMC musculoskeletal disorders · 2026Observational
- Association of serum 25-hydroxyvitamin D levels with fatigue severity in adults: A cross-sectional study.Northern clinics of Istanbul · 2026Article
- Assessment of Vitamin D Deficiency and its Association with Musculoskeletal Pain in Children.Journal of pharmacy & bioallied sciences · 2025Article
- Increased risk of uterine leiomyoma among women with migraine in reproductive age.Scientific reports · 2025Article
- Evaluation of serum Vitamin-D levels in non-specific chronic musculoskeletal pain.Bioinformation · 2025Article
- Severity of premenstrual symptoms among women with musculoskeletal pain: relation to vitamin D, calcium, and psychological symptoms.Journal of medicine and life · 2024Article
- Review
- New evidence that vitamin D prevents headache: a bidirectional two-sample Mendelian randomization analysis.Frontiers in neurology · 2024Article
- Cross-Sectional Study of Serum Vitamin B12 and Vitamin D3 Levels Amongst Corporate Employees.Cureus · 2023Article
- Dry Eye Disease: What Is the Role of Vitamin D?International journal of molecular sciences · 2023Review
- Vitamin D in Neurological Diseases.International journal of molecular sciences · 2022Review
- Review
- Review on Headache Related to Dietary Supplements.Current pain and headache reports · 2022Review
10 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate vitamin D levels in patients with non-specific musculoskeletal pain, headache, and fatigue.
designA cross-sectional descriptive study.
settingA health center in Oslo, Norway, with a multi-ethnic population. SUBJECTS: A total of 572 patients referred by a general practitioner (GP) for an examination of hypovitaminosis D who reported musculoskeletal pain, headache, or fatigue. The patients' native countries were: Norway (n = 249), Europe, America, and South-East Asia (n = 83), and the Middle East, Africa, and South Asia (n = 240). Both genders and all ages were included.
main outcome measuresVitamin D levels (25-hydroxyvitamin D) in nmol/L.
resultsHypovitaminosis D (25-hydroxyvitamin D < 50 nmol/L) was found in 58% of patients. One-third of ethnic Norwegians had hypovitaminosis D, while 83% of patients from the Middle East, Africa, and South Asia had hypovitaminosis D with minimal seasonal variation of levels. One in two women from these countries had a vitamin D level below 25 nmol/L. Mean vitamin D level was lower in patients with headaches compared with patients with other symptoms. Some 15% of patients with low (< 50 nmol/L) vitamin D levels reported headaches, compared with 5% of those with normal vitamin D levels.
conclusionOur study shows a high prevalence of hypovitaminosis D in patients with non-specific musculoskeletal pain, headache, or fatigue for whom the GP had suspected a low vitamin D level. Hypovitaminosis D was not restricted to immigrant patients. These results indicate that GPs should maintain awareness of hypovitaminosis D and refer patients who report headaches, fatigue, and musculoskeletal pain with minimal sun exposure and a low dietary vitamin D intake for assessment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.