ArticleApplied and environmental microbiology2010
Accidental selection and intentional restoration of sporulation-deficient Bacillus anthracis mutants.
Article in Applied and environmental microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Phosphorelay changes and plasticity underlie the life history evolution ofMicrobiology (Reading, England) · 2025Article
- Laboratory strains of Bacillus anthracis lose their ability to rapidly grow and sporulate compared to wildlife outbreak strains.PloS one · 2020Article
- Emergence of a non-sporulating secondary phenotype in Clostridium (Clostridioides) difficile ribotype 078 isolated from humans and animals.Scientific reports · 2019Article
- Cell Death Pathway That Monitors Spore Morphogenesis.Trends in microbiology · 2017Review
- A Quality-Control Mechanism Removes Unfit Cells from a Population of Sporulating Bacteria.Developmental cell · 2015Article
- Bacillus cereus G9241 S-layer assembly contributes to the pathogenesis of anthrax-like disease in mice.Journal of bacteriology · 2013Article
- The Clostridium difficile spo0A gene is a persistence and transmission factor.Infection and immunity · 2012Article
- Occurrence, recognition, and reversion of spontaneous, sporulation-deficient Bacillus anthracis mutants that arise during laboratory culture.Microbes and infection · 2012Review
- A Bacillus anthracis strain deleted for six proteases serves as an effective host for production of recombinant proteins.Protein expression and purification · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
We demonstrate the frequent accidental enrichment of spontaneous sporulation-deficient mutants of Bacillus anthracis on solid medium and identify contributing factors. Mutations in spo0A, encoding the master regulator of sporulation initiation, were found in 38 of 53 mutants. Transductions using bacteriophage CP51 propagated on sporogenic bacteria allowed for the restoration of sporulation phenotypes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.