ArticleJournal of bacteriology2010
The paralogous MarR/DUF24-family repressors YodB and CatR control expression of the catechol dioxygenase CatE in Bacillus subtilis.
Article in Journal of bacteriology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 32 citations in OpenAlex.
- SydR, a redox-sensing MarR-type regulator ofmBio · 2024Article
- MarR Family Transcriptional Regulators and Their Roles in Plant-Interacting Bacteria.Microorganisms · 2023Review
- Antibiotic profiling of wild-type bacilli led to the discovery of new lanthipeptide subtilin-producing Bacillus spizizenii strains whose 16S rDNA sequences differ from the B. spizizenii typing strain.International microbiology : the official journal of the Spanish Society for Microbiology · 2022Article
- Bacterial degradation of the anti-depressant drug fluoxetine produces trifluoroacetic acid and fluoride ion.Applied microbiology and biotechnology · 2021Article
- Manganese impairs the QoxABCD terminal oxidase leading to respiration-associated toxicity.Molecular microbiology · 2021Article
- The MarR-Type Repressor MhqR Confers Quinone and Antimicrobial Resistance inAntioxidants & redox signaling · 2019Article
- The Disulfide Stress Response and ProteinAntioxidants (Basel, Switzerland) · 2019Article
- Roles and regulation of Spx family transcription factors in Bacillus subtilis and related species.Advances in microbial physiology · 2019Review
- Article
- Redox-Sensing Under Hypochlorite Stress and Infection Conditions by the Rrf2-Family Repressor HypR in Staphylococcus aureus.Antioxidants & redox signaling · 2018Article
- Evolution of Antibiotic Resistance without Antibiotic Exposure.Antimicrobial agents and chemotherapy · 2017Article
- Two distinct mechanisms of transcriptional regulation by the redox sensor YodB.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Thiol-based redox switches in prokaryotes.Biological chemistry · 2015Review
- Microbial surfactant mediated degradation of anthracene in aqueous phase by marineBiotechnology reports (Amsterdam, Netherlands) · 2014Article
- A dual role of the transcriptional regulator TstR provides insights into cyanide detoxification in Lactobacillus brevis.Molecular microbiology · 2014Article
- Genomic reconstruction of the transcriptional regulatory network in Bacillus subtilis.Journal of bacteriology · 2013Article
- Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Structural insights into the redox-switch mechanism of the MarR/DUF24-type regulator HypR.Nucleic acids research · 2012Article
- MarR-type transcriptional regulator ChlR activates expression of tetrapyrrole biosynthesis genes in response to low-oxygen conditions in cyanobacteria.The Journal of biological chemistry · 2012Article
- S-bacillithiolation protects against hypochlorite stress in Bacillus subtilis as revealed by transcriptomics and redox proteomics.Molecular & cellular proteomics : MCP · 2011Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The redox-sensing MarR/DUF24-type repressor YodB controls expression of the azoreductase AzoR1 and the nitroreductase YodC that are involved in detoxification of quinones and diamide in Bacillus subtilis. In the present paper, we identified YodB and its paralog YvaP (CatR) as repressors of the yfiDE (catDE) operon encoding a catechol-2,3-dioxygenase that also contributes to quinone resistance. Inactivation of both CatR and YodB is required for full derepression of catDE transcription. DNA-binding assays and promoter mutagenesis studies showed that CatR protects two inverted repeats with the consensus sequence TTAC-N(5)-GTAA overlapping the -35 promoter region (BS1) and the transcriptional start site (TSS) (BS2). The BS1 operator was required for binding of YodB in vitro. CatR and YodB share the conserved N-terminal Cys residue, which is required for redox sensing of CatR in vivo as shown by Cys-to-Ser mutagenesis. Our data suggest that CatR is modified by intermolecular disulfide formation in response to diamide and quinones in vitro and in vivo. Redox regulation of CatR occurs independently of YodB, and no protein interaction was detected between CatR and YodB in vivo using protein cross-linking and mass spectrometry.
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