Evidence map›Paper›PMID 20638884›Full record

Trial reportInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2010

The effect of Helicobacter pylori infection on growth velocity in young children from poor urban communities in Ecuador.

Andrey I Egorov, Fernando Sempértegui, Bertha Estrella, Josefina Egas, Elena N Naumova, Jeffrey K Griffiths

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Effect of Saccharomyces boulardii CNCM I-745 as complementary treatment of Helicobacter pylori infection on gut microbiome.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
  3. Association ofThe American journal of tropical medicine and hygiene · 2020
    Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Andrey I EgorovUS Environmental Protection Agency, National Center for Environmental Assessment, 26 W. Martin Luther King Drive, MS A110, Cincinnati, OH 45268, USA. andrey.egorov@tufts.edu
Fernando Sempértegui
Bertha Estrella
Josefina Egas
Elena N Naumova
Jeffrey K Griffiths
Central University of Ecuador · ECTufts University · USEnvironmental Protection Agency · USPontificia Universidad Católica del Ecuador · EC

Funding

VITAMIN A/ZINC--PREVENTION OF PNEUMONIA (VAZPOP) STUDYR01HD038327 · NICHD · TUFTS UNIVERSITY BOSTON · PI GRIFFITHS, JEFFREY K · 2000 to 2004
$2.3M
NICHD NIH HHS R01 HD038327NICHD NIH HHS R01 HD38327
6 · The paper itself

Abstract

objectiveTo characterize the potential effects of Helicobacter infections on growth velocity in low socioeconomic status young children in a developing country.

methodsChildren were recruited in poor suburbs of Quito, Ecuador. Normally nourished, mildly and substantially malnourished children (defined using weight-for-age Z-scores at recruitment) formed equal strata. Six height and weight measurements were collected during one year. Enrollment and exit serum samples were analyzed for anti-Helicobacter IgG and exit non-diarrheal feces tested for Helicobacter antigen.

resultsAmong 124 participants (enrollment age 19 ± 9 months), 76 (61%) excreted fecal antigen at exit (were infected). Of these, 44 were seropositive at least once (chronic infections) and 32 tested seronegative both times (new or acute phase infections). The adjusted linear growth velocity during follow-up in children with new infections was reduced by 9.7 (3.8, 15.6) mm/year compared to uninfected controls and 6.4 (0.0, 12.9) mm/year compared to children with chronic infections. The effects of Helicobacter infections on ponderal growth were not significant.

conclusionThese results suggest that linear growth velocity is reduced in young children during the initial phase of Helicobacter infection.

Indexed as

PovertyUrban PopulationAcute DiseaseAntigens, BacterialBody HeightBody WeightChild, PreschoolChronic DiseaseEcuadorFecesFemaleGrowth DisordersHelicobacter InfectionsHelicobacter pyloriHumansInfantAntigens, Bacterial

Identifiers

PMID20638884
PMCPMC8527551
OpenAlexW2057461314

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.