Evidence map›Paper›PMID 20638644›Full record

ReviewCell host & microbe2010

Cytoplasmic viral replication complexes.

Johan A den Boon, Arturo Diaz, Paul Ahlquist

Open access · bronzeAbstract readReview
In one paragraph

Review in Cell host & microbe, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 215 papers.

0numbers the graph read from it
0cells of the map it votes in
215citing papers in PubMed
29.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

215 citing papers in PubMed, 339 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Discovery of the order 'Virus evolution · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Potential effect ofFrontiers in microbiology · 2025
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Flavivirus Concentrates Host ER in Main Replication Compartments to Facilitate Replication.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  19. Article
  20. The Formation and Function ofInternational journal of molecular sciences · 2023
    Review

155 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Johan A den BoonInstitute for Molecular Virology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Arturo Diaz
Paul Ahlquist
University of Wisconsin–Madison · USHoward Hughes Medical Institute · US

Funding

Virology Training ProgramT32AI078985 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI LAMBERT, PAUL F. · 2009 to 2018
$3.3M
GENE FUNCTIONS AND MOLECULAR GENETICS OF RNA VIRUSESR37GM035072 · NIGMS · UNIVERSITY OF WISCONSIN MADISON · PI AHLQUIST, PAUL G. · 1995 to 2004
$1.9M
GENE FUNCTIONS AND MOLECULAR GENETICS OF RNA VIRUSESR01GM035072 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI AHLQUIST, PAUL G. · 1985 to 2009
$1.6M
Howard Hughes Medical InstituteNIAID NIH HHS T32 AI078985NIGMS NIH HHS GM35072NIGMS NIH HHS R01 GM035072NIGMS NIH HHS R37 GM035072
6 · The paper itself

Abstract

Many viruses that replicate in the cytoplasm compartmentalize their genome replication and transcription in organelle-like structures that enhance replication efficiency and protection from host defenses. In particular, recent studies with diverse positive-strand RNA viruses have further elucidated the ultrastructure of membrane-bound RNA replication complexes and how these complexes function in close coordination with virion assembly and budding. The structure, function, and assembly of some positive-strand RNA virus replication complexes have parallels and potential evolutionary links with the replicative cores of double-strand RNA virus and retrovirus virions and more general similarities with the replication factories of cytoplasmic DNA viruses.

Indexed as

Virus Physiological PhenomenaVirus ReplicationAnimalsCytoplasmHumansVirionVirus DiseasesViruses

Identifiers

PMID20638644
PMCPMC2921950
OpenAlexW2093373040

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.