ArticleNursing outlook
Changes in the institutional review board submission process for multicenter research over 6 years.
Article in Nursing outlook. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Increasing burden of institutional review in multicenter clinical trials of infertility: the Reproductive Medicine Network experience with the Pregnancy in Polycystic Ovary Syndrome (PPCOS) I and II studies.Fertility and sterility · 2011Trial
- Evaluation of a University's Institutional Review Board Based on Campus Feedback: A Cross-Sectional Study.Cureus · 2019Article
- The IRB structure and medical research reform.Clinical and translational medicine · 2018Article
- Navigating the Institutional Review Board (IRB) Process for Pharmacy-Related Research.Hospital pharmacy · 2017Article
- Time required to review research protocols at 10 Veterans Affairs Institutional Review Boards.The Journal of surgical research · 2016Article
- Prioritizing Initiatives for Institutional Review Board (IRB) Quality Improvement.AJOB empirical bioethics · 2016Article
- Improving the Proficiency of Research Consent Administrators.Clinical and translational science · 2015Article
- Time required for institutional review board review at one Veterans Affairs medical center.JAMA surgery · 2015Article
- Expanding research to provide an evidence base for nutritional interventions for the management of inborn errors of metabolism.Molecular genetics and metabolism · 2013Article
- How variability in the institutional review board review process affects minimal-risk multisite health services research.Annals of internal medicine · 2012Article
- Burdens on research imposed by institutional review boards: the state of the evidence and its implications for regulatory reform.The Milbank quarterly · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Although collaborative research across sites is essential to increase the statistical power and generalizability of research findings, the need to undergo multiple institutional review board (IRB) reviews is a challenge. The purposes of this paper are to describe changes in the IRB submission process in 2 national multisite studies before and after the implementation of the Health Information Portability and Accountability Act (HIPAA) Privacy rule (2002 and 2008) and to discuss implications for policy and practice related to human subjects research. In the second study, there was a shorter mean approval time and reduced variability in the decision about the level of review, the mean number of pages per application doubled, and an increased proportion of IRBs required conflict of interest and data use agreements. Possible approaches to further enhance the efficiency and streamlining of the research review process are suggested.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.