Evidence map›Paper›PMID 20636810›Full record

ReviewImmunological reviews2010

Immune memory redefined: characterizing the longevity of natural killer cells.

Joseph C Sun, Joshua N Beilke, Lewis L Lanier

Abstract readReview
In one paragraph

Review in Immunological reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed.

  1. Article
  2. Review
  3. Food science & nutrition · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Advances in NK cell production.Cellular & molecular immunology · 2022
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joseph C SunDepartment of Microbiology and Immunology and the Cancer Research Institute, University of California, San Francisco, CA 94143, USA.
Joshua N Beilke
Lewis L Lanier

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
NK Cells and HIV InfectionP01AI064520 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BRODSKY, FRANCES M. · 2005 to 2009
$6.2M
NK MemoryR01AI068129 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LANIER, LEWIS LEE · 2006 to 2020
$6.0M
NK and T Cell Costimulation by NKG2D/DAP10R37AI066897 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LANIER, LEWIS LEE · 2006 to 2015
$3.8M
RAE-1 Family of Proteins in Innate and Adaptive ImmunityR01CA095137 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LANIER, LEWIS LEE · 2003 to 2013
$2.9M
NCI NIH HHS CA095137NCI NIH HHS R01 CA095137NIAID NIH HHS AI066897NIAID NIH HHS AI068129NIAID NIH HHS AI64520NIAID NIH HHS P01 AI064520NIAID NIH HHS P30 AI027763NIAID NIH HHS R01 AI068129NIAID NIH HHS R37 AI066897
6 · The paper itself

Abstract

Natural killer (NK) cells respond rapidly to transformed, stressed, or virally infected cells and provide a first-line immune defense against pathogen invasion and cancer. Thought to involve short-lived effector cells that are armed for battle, NK cells were not previously known to contribute in recall responses to pathogen re-encounter. Here, we highlight recent discoveries demonstrating that NK cells are not limited to driving primary immune responses to foreign antigen but can mount secondary responses contributing to immune memory. We also further characterize the phenotype and function of long-lived memory NK cells generated during viral infection.

Indexed as

Adaptive ImmunityAnimalsHumansImmunologic MemoryKiller Cells, NaturalModels, ImmunologicalTime FactorsT-Lymphocytes, CytotoxicVirus Diseases

Identifiers

PMID20636810
PMCPMC2907527

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.