ArticleStroke2010
Alcohol and acute ischemic stroke onset: the stroke onset study.
Article in Stroke, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Alcohol and Immediate Risk of Cardiovascular Events: A Systematic Review and Dose-Response Meta-Analysis.Circulation · 2016Pooled it
- Outbursts of anger as a trigger of acute cardiovascular events: a systematic review and meta-analysis.European heart journal · 2014Pooled it
- Trigger factors in patients with a patent foramen ovale-associated stroke: A case-crossover study.International journal of stroke : official journal of the International Stroke Society · 2024Article
- Polypharmacy in atrial fibrillation: A prospective analysis of mortality and ischemic stroke using the Clinical Practice Research Datalink.Journal of arrhythmia · 2024Article
- Cigarette smoking as a risk factor for ischaemic stroke in young South Asian male migrants to Qatar: The BRAINS study.Qatar medical journal · 2023Article
- Photoacoustic imaging for in vivo quantification of alcohol-induced structural and functional changes in cerebral vasculature in high alcohol-preferring mice (HAP).Alcohol (Fayetteville, N.Y.) · 2022Article
- Effect of Cerebral Ischemic Strokes in Different Cerebral Artery Regions on Left Ventricular Function.Frontiers in cardiovascular medicine · 2022Article
- Association between the Suita Score and Stroke Recurrence in Patients with First-ever Ischemic Stroke: A Prospective Cohort Study.Internal medicine (Tokyo, Japan) · 2022Article
- TSPO polymorphism in individuals with alcohol use disorder: Association with cholesterol levels and withdrawal severity.Addiction biology · 2021Article
- Article
- Activation of NLRP3 inflammasome by cholesterol crystals in alcohol consumption induces atherosclerotic lesions.Brain, behavior, and immunity · 2017Article
- Modelling the impact of alcohol consumption on cardiovascular disease mortality for comparative risk assessments: an overview.BMC public health · 2016Article
- Risk of myocardial infarction immediately after alcohol consumption.Epidemiology (Cambridge, Mass.) · 2015Article
- Exchangeability in the case-crossover design.International journal of epidemiology · 2014Article
- Relation of outbursts of anger and risk of acute myocardial infarction.The American journal of cardiology · 2013Article
- Self-Care Self-Efficacy, Religious Participation and Depression as Predictors of Poststroke Self-Care Among Underserved Ethnic Minorities.Health psychology research · 2013Article
- Chronic vascular risk factors (cholesterol, homocysteine, ethanol) impair spatial memory, decline cholinergic neurons and induce blood-brain barrier leakage in rats in vivo.Journal of the neurological sciences · 2012Article
- Purine-rich foods intake and recurrent gout attacks.Annals of the rheumatic diseases · 2012Article
- Effects of long-term moderate ethanol and cholesterol on cognition, cholinergic neurons, inflammation, and vascular impairment in rats.Neuroscience · 2012Article
- Physical, psychological and chemical triggers of acute cardiovascular events: preventive strategies.Circulation · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
background and purposePrevious research suggests that regular heavy alcohol consumption increases the risk for ischemic stroke, whereas frequent light to moderate alcohol intake may decrease the risk. However, the risk of ischemic stroke associated with transient exposure to alcohol remains unclear. In this study, we used a case-crossover approach to test the hypothesis that alcohol consumption affects the acute risk of ischemic stroke, to determine the length of time between alcohol intake and the onset of symptoms (induction time), and to examine whether the risk varies by the type of alcohol.
methodsIn this multicenter study, we interviewed 390 patients (209 men, 181 women) between January 2001 and November 2006 (median 3 days after stroke). Alcohol consumption in the hour before stroke symptoms was compared with its expected frequency based on the usual frequency of alcohol consumption over the prior year.
resultsOf the 390 patients, 248 (64%) reported alcohol consumption in the prior year, 104 within 24 hours and 14 within 1 hour of stroke onset. The relative risk of stroke in the hour after consuming alcohol was 2.3 (95% CI, 1.4 to 4.0; P=0.002). The relative risks were similar for different types of alcoholic beverages and when the sample was restricted to those who were not simultaneously exposed to other potential triggers.
conclusionsThe risk of stroke onset is transiently elevated in the hour after alcohol ingestion.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.