Trial reportStroke2010
The ARUBA trial: current status, future hopes.
Trial report in Stroke, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 80 citations in OpenAlex.
- Medical management with or without interventional therapy for unruptured brain arteriovenous malformations (ARUBA): a multicentre, non-blinded, randomised trial.Lancet (London, England) · 2014Trial
- Comparative Study of Automated Algorithms for Brain Arteriovenous Malformation Nidus Extent Identification Using 3DRA.Cardiovascular engineering and technology · 2023Article
- National reduction in cerebral arteriovenous malformation treatment correlated with increased rupture incidence.Journal of neurointerventional surgery · 2023Article
- Ruptured bilateral brain arteriovenous malformations in a young woman with early pregnancy: a case report.Journal of medical case reports · 2023Article
- Impact of Pre-operative Embolization With Onyx for Brain Arteriovenous Malformation Surgery.Frontiers in neurology · 2022Article
- Cellular loci involved in the development of brain arteriovenous malformations.Frontiers in human neuroscience · 2022Review
- The role of mural cells in hemorrhage of brain arteriovenous malformation.Brain hemorrhages · 2021Article
- Recent Advances in Basic Research for Brain Arteriovenous Malformation.International journal of molecular sciences · 2019Review
- A proposed classification for assessing rupture risk in patients with intracranial arteriovenous malformations.Surgical neurology international · 2017Article
- Vascular Integrity in the Pathogenesis of Brain Arteriovenous Malformation.Acta neurochirurgica. Supplement · 2016Review
- Management of unbled brain arteriovenous malformation study.Neurologic clinics · 2015Review
- Current surgical results with low-grade brain arteriovenous malformations.Journal of neurosurgery · 2015Article
- Animal Models in Studying Cerebral Arteriovenous Malformation.BioMed research international · 2015Review
- Endovascular treatment of brain arteriovenous malformations using a liquid embolic agent: results of a prospective, multicentre study (BRAVO).European radiology · 2013Observational
- Diagnosis and treatment of arteriovenous malformations.Current neurology and neuroscience reports · 2013Review
- Obliterating the Seizure Focus in AVMs is Effective: More Clinical Data Confirming Common Sense.Epilepsy currents · 2013Article
- Hemodynamic changes in patients with arteriovenous malformations assessed using high-resolution 3D radial phase-contrast MR angiography.AJNR. American journal of neuroradiology · 2012Article
- Management of ruptured brain arteriovenous malformations.Current atherosclerosis reports · 2012Review
- Etiologies of intracerebral hematomas.Current atherosclerosis reports · 2012Review
- Trends in the management of intracranial vascular malformations in the USA from 2000 to 2007.Stroke research and treatment · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 2 institutions in 2 countries.
Funding
Abstract
background and purposeReport on the status of an on-going National Institutes of Neurological Disorders and Stroke (NINDS)-supported clinical trial of management of unbled brain arteriovenous malformations. SUMMARY OF REVIEW: Begun in April 2007 with 3 centers, the trial has grown to 65 centers, and has randomized 124 patients through mid-June 2010 en route to the planned 400. The current literature continues to support the rationale for the trial.
conclusionsARUBA is steadily approaching its monthly randomization goals and has already reached the number needed to test the maximum published interventional complication rates against the minimum hemorrhage rates for natural history.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.