ArticlePlant physiology2010
A metabolomic approach to study major metabolite changes during acclimation to limiting CO2 in Chlamydomonas reinhardtii.
Article in Plant physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 84 citations in OpenAlex.
- The mosaic of aquatic photorespiration: evolution, diversity, and global biogeochemical impacts.The New phytologist · 2026Review
- Time-dependent metabolic reprogramming in Scenedesmus sp. induced by intermittently sparged COScientific reports · 2026Article
- Photosynthetic Electron Flows and Networks of Metabolite Trafficking to Sustain Metabolism in Photosynthetic Systems.Plants (Basel, Switzerland) · 2024Review
- Intracellular metabolomic profiling of Picochlorum sp. under diurnal conditions mimicking outdoor light, temperature, and seasonal variations.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Metabolomic response to high light from pgrl1 and pgr5 mutants of Chlamydomonas reinhardtii.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023Article
- Palmelloid Formation and Cell Aggregation Are Essential Mechanisms for High Light Tolerance in a Natural Strain ofInternational journal of molecular sciences · 2023Article
- Metabolomic Study of Heterotrophically GrownMolecules (Basel, Switzerland) · 2021Article
- Lipid Remodeling Reveals the Adaptations of a Marine Diatom to Ocean Acidification.Frontiers in microbiology · 2021Article
- Effect of Acetaminophen (APAP) on Physiological Indicators inLife (Basel, Switzerland) · 2020Article
- Elucidation and genetic intervention of COJournal of biosciences · 2020Article
- Photosynthetic Carbon Partitioning and Metabolic Regulation in Response to Very-Low and High COFrontiers in plant science · 2020Article
- Improved Algal Toxicity Test System for RobustMetabolites · 2019Article
- Metabolic responses to drought stress in the tissues of drought-tolerant and drought-sensitive wheat genotype seedlings.AoB PLANTS · 2018Article
- Bicarbonate Induced Redox Proteome Changes in Arabidopsis Suspension Cells.Frontiers in plant science · 2017Article
- Metabolomic Responses of Arabidopsis Suspension Cells to Bicarbonate under Light and Dark Conditions.Scientific reports · 2016Article
- Crystal structure and functional characterization of photosystem II-associated carbonic anhydrase CAH3 in Chlamydomonas reinhardtii.Plant physiology · 2015Article
- Effect of salinity stress on plants and its tolerance strategies: a review.Environmental science and pollution research international · 2015Review
- Article
- Dynamic metabolic profiling of the marine microalga Chlamydomonas sp. JSC4 and enhancing its oil production by optimizing light intensity.Biotechnology for biofuels · 2015Article
- Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Using a gas chromatography-mass spectrometry-time of flight technique, we determined major metabolite changes during induction of the carbon-concentrating mechanism in the unicellular green alga Chlamydomonas reinhardtii. In total, 128 metabolites with significant differences between high- and low-CO(2)-grown cells were detected, of which 82 were wholly or partially identified, including amino acids, lipids, and carbohydrates. In a 24-h time course experiment, we show that the amino acids serine and phenylalanine increase transiently while aspartate and glutamate decrease after transfer to low CO(2). The biggest differences were typically observed 3 h after transfer to low-CO(2) conditions. Therefore, we made a careful metabolomic examination at the 3-h time point, comparing low-CO(2) treatment to high-CO(2) control. Five metabolites involved in photorespiration, 11 amino acids, and one lipid were increased, while six amino acids and, interestingly, 21 lipids were significantly lower. Our conclusion is that the metabolic pattern during early induction of the carbon-concentrating mechanism fit a model where photorespiration is increasing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.