Evidence map›Paper›PMID 20634392›Full record

ReviewCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2011

Tuberculosis: evidence review for newly arriving immigrants and refugees.

Christina Greenaway, Amelia Sandoe, Bilkis Vissandjee, Ian Kitai, Doug Gruner, Wendy Wobeser, Kevin Pottie, Erin Ueffing, Dick Menzies, Kevin Schwartzman and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 6 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 6 syntheses or guidelines pooled it, 114 citations in OpenAlex.

  1. Pooled it
  2. The effectiveness and cost-effectiveness of screening for active tuberculosis among migrants in the EU/EEA: a systematic review.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018
    Pooled it
  3. The effectiveness and cost-effectiveness of screening for latent tuberculosis among migrants in the EU/EEA: a systematic review.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018
    Pooled it
  4. Pooled it
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  7. Article
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  14. Demographic Control Measure Implications of Tuberculosis Infection for Migrant Workers across Taiwan Regions.International journal of environmental research and public health · 2022
    Article
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  16. How Well Does TSTin3D Predict Risk of Active Tuberculosis in the Canadian Immigrant Population? An External Validation Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
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  17. Article
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Christina GreenawayDivision of Infectious Diseases and Clinical Epidemiology and Community Services Unit, SMBD Jewish General Hospital, McGill University, Montréal, Que. ca.greenaway@mcgill.ca
Amelia Sandoe
Bilkis Vissandjee
Ian Kitai
Doug Gruner
Wendy Wobeser
Kevin Pottie
Erin Ueffing
Dick Menzies
Kevin Schwartzman
Canadian Collaboration for Immigrant and Refugee Health
Jewish General Hospital · CAUniversité de Montréal · CAUniversity of Toronto · CAMcGill University · CAQueen's University · CAUniversity of Ottawa · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

backgroundThe foreign-born population bears a disproportionate health burden from tuberculosis, with a rate of active tuberculosis 20 times that of the non-Aboriginal Canadian-born population, and could therefore benefit from tuberculosis screening programs. We reviewed evidence to determine the burden of tuberculosis in immigrant populations, to assess the effectiveness of screening and treatment programs for latent tuberculosis infection, and to identify potential interventions to improve effectiveness.

methodsWe performed a systematic search for evidence of the burden of tuberculosis in immigrant populations and the benefits and harms, applicability, clinical considerations, and implementation issues of screening and treatment programs for latent tuberculosis infection in the general and immigrant populations. The quality of this evidence was assessed and ranked using the GRADE approach (Grading of Recommendations Assessment, Development and Evaluation).

resultsChemoprophylaxis with isoniazid is highly efficacious in decreasing the development of active tuberculosis in people with latent tuberculosis infection who adhere to treatment. Monitoring for hepatotoxicity is required at all ages, but close monitoring is required in those 50 years of age and older. Adherence to screening and treatment for latent tuberculosis infection is poor, but it can be increased if care is delivered in a culturally sensitive manner.

interpretationImmigrant populations have high rates of active tuberculosis that could be decreased by screening for and treating latent tuberculosis infection. Several patient, provider and infrastructure barriers, poor diagnostic tests, and the long treatment course, however, limit effectiveness of current programs. Novel approaches that educate and engage patients, their communities and primary care practitioners might improve the effectiveness of these programs.

Indexed as

Emigrants and ImmigrantsPractice Guidelines as TopicRefugeesCanadaEvidence-Based MedicineHumansMass ScreeningTuberculosis

Identifiers

PMID20634392
PMCPMC3168670
OpenAlexW2109199066

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.