Trial reportFertility and sterility2011
Magnetic resonance elastography of uterine leiomyomas: a feasibility study.
Trial report in Fertility and sterility, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Magnetic resonance elastography (MRE) for the evaluation of fibrosis in patients with benign uterine disorders: a systematic review.Abdominal radiology (New York) · 2026Pooled it
- Evaluation of stiffness values of normal uterine myometrium by 3T magnetic resonance elastography.Frontiers in medicine · 2026Article
- 3D vector MR elastography applications in small organs.Magnetic resonance imaging · 2024Review
- Multiparametric quantitative magnetic resonance imaging of uterine fibroids for prediction of growth rate-a pilot study.Quantitative imaging in medicine and surgery · 2024Article
- Tumor stiffness measured by 3D magnetic resonance elastography can help predict the aggressiveness of endometrial carcinoma: preliminary findings.Cancer imaging : the official publication of the International Cancer Imaging Society · 2021Article
- Uterine leiomyomas: correlation between histologic composition and stiffness via magnetic resonance elastography - a Pilot Study.Ginekologia polska · 2020Article
- MR-guided Focused Ultrasound for Uterine Fibroids: A Preliminary Study of Relationship between the Treatment Outcomes and Factors of MR Images Including Elastography.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2019Article
- Soft tissue elastography via shearing interferometry.Journal of medical imaging (Bellingham, Wash.) · 2018Article
- New and Emerging Applications of Magnetic Resonance Elastography of Other Abdominal Organs.Topics in magnetic resonance imaging : TMRI · 2018Review
- Uterine fibroids: correlations between MRI appearance and stiffness via magnetic resonance elastography.Abdominal radiology (New York) · 2018Article
- Large-field-of-view optical elastography using digital image correlation for biological soft tissue investigation.Journal of medical imaging (Bellingham, Wash.) · 2017Article
- Magnetic resonance elastography (MRE) in cancer: Technique, analysis, and applications.Progress in nuclear magnetic resonance spectroscopy · 2015Review
- Magnetic resonance elastography of abdomen.Abdominal imaging · 2015Review
- In vivo high-resolution magnetic resonance elastography of the uterine corpus and cervix.European radiology · 2014Article
- Leiomyoma cells in 3-dimensional cultures demonstrate an attenuated response to fasudil, a rho-kinase inhibitor, when compared to 2-dimensional cultures.Reproductive sciences (Thousand Oaks, Calif.) · 2014Article
- The extracellular matrix contributes to mechanotransduction in uterine fibroids.Obstetrics and gynecology international · 2014Review
- Acoustic waves in medical imaging and diagnostics.Ultrasound in medicine & biology · 2013Review
- A novel saline infusion sonohysterography-based strain imaging approach for evaluation of uterine abnormalities in vivo: preliminary results.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2012Article
- Characterization of tissue biomechanics and mechanical signaling in uterine leiomyoma.Matrix biology : journal of the International Society for Matrix Biology · 2012Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveTo determine the feasibility of performing in vivo magnetic resonance elastography (MRE) for uterine leiomyoma.
designPilot study.
settingAcademic medical center. PATIENT(S): Six subjects planning surgical excision of uterine leiomyomas. INTERVENTION(S): MRE before planned surgery. MAIN OUTCOME MEASURE(S): Achieving an appropriate phase signal-to-noise ratio (PSNR) in the leiomyoma to allow assessment of leiomyoma elasticity in kilopascals (kPa). RESULT(S): MRE was successful in all subjects for uteri ranging from 100 to >1,000 g. Subjects had body mass indexes ranging from 23.0 to 38.0 kg/m2. Appropriate PSNRs, ranging from 5.45 to 42.28, were achieved for leiomyomas in all subjects. Mean elasticity of uterine leiomyomas ranged from 3.95 to 6.68 kPa. CONCLUSION(S): MRE is a feasible technique for studying the in vivo mechanical properties of uterine leiomyomas and demonstrates significant heterogeneity in elasticity between lesions. Further work is necessary to optimize the technique and understand the clinical utility of this technique for women with uterine leiomyomas.
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