Trial reportBehavioral and brain functions : BBF2010
Does the cortisol response to stress mediate the link between expressed emotion and oppositional behavior in Attention-Deficit/Hyperactivity-Disorder (ADHD)?
Trial report in Behavioral and brain functions : BBF, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Cortisol and inflammatory biomarker levels in youths with attention deficit hyperactivity disorder (ADHD): evidence from a systematic review with meta-analysis.Translational psychiatry · 2021Pooled it
- Expressed Emotion in the Family: A Meta-Analytic Review of Expressed Emotion as a Mechanism of the Transgenerational Transmission of Mental Disorders.Frontiers in psychiatry · 2021Pooled it
- Associations between Computationally Derived Parent Emotional Sentiment Scores and Child ADHD and ODD Over Time.Research on child and adolescent psychopathology · 2024Article
- Behavioral, Hormonal, and Serotonergic Responses to Different Restricted Feeding Schedules in Rats.International journal of tryptophan research : IJTR · 2022Article
- Temperament Dimensions and Awakening Cortisol Levels in Attention-Deficit/Hyperactivity Disorder.Frontiers in psychiatry · 2022Article
- Parental positive regard and expressed emotion-prediction of developing attention deficit, oppositional and callous unemotional problems between preschool and school age.European child & adolescent psychiatry · 2021Article
- Prevalence of ADHD in Accident Victims: Results of the PRADA Study.Journal of clinical medicine · 2019Article
- Parental criticism and behavior problems in children with autism spectrum disorder.Autism : the international journal of research and practice · 2019Article
- Predicting attention-deficit/hyperactivity disorder severity from psychosocial stress and stress-response genes: a random forest regression approach.Translational psychiatry · 2017Article
- Parental Expressed Emotion and Youth Psychopathology: New Directions for an Old Construct.Child psychiatry and human development · 2015Review
- Attachment and parental reflective functioning features in ADHD: enhancing the knowledge on parenting characteristics.Frontiers in psychology · 2015Article
- Differential effects of anxiety and depressive symptoms on working memory components in children and adolescents with ADHD combined type and ADHD inattentive type.European child & adolescent psychiatry · 2014Article
- Slow cortical potential neurofeedback and self-management training in outpatient care for children with ADHD: study protocol and first preliminary results of a randomized controlled trial.Frontiers in human neuroscience · 2014Article
- One problem is the risk of the next: a vote for early detection and preventive intervention of coexisting psychopathology.European child & adolescent psychiatry · 2012Article
- Family environment and behavior problems in children, adolescents, and adults with fragile X syndrome.American journal on intellectual and developmental disabilities · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundExpressed Emotions (EE) are associated with oppositional behavior (OPB) in children with Attention Deficit/Hyperactivity Disorder (ADHD). EE has been linked to altered stress responses in some disorders, but ADHD has not been studied. We test the hypothesis that OPB in ADHD is mediated by altered stress-related cortisol reactivity to EE.
methodsTwo groups of children (with/without ADHD) and their respective parents were randomly assigned to two different conditions with/without negative emotion and participated in an emotion provocation task. Parents' EE, their ratings of their children's OPB and their children's salivary cortisol levels were measured.
resultsLow parental warmth was associated with OPB in ADHD. High levels of parental EE elicited a larger cortisol response. Stress-related cortisol reactivity mediated the EE-OPB link for all children. This highlights the general importance of parent-child interactions on externalizing behavior problems.
conclusionHigh EE is a salient stressor for ADHD children that leads to increased levels of cortisol and OPB. The development of OPB might be mediated by the stress-response to high EE.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.