ArticleMedical physics2010
Age- and race-dependence of the fibroglandular breast density analyzed on 3D MRI.
Article in Medical physics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 39 citations in OpenAlex.
- Double-Blind Randomized 12-Month Soy Intervention Had No Effects on Breast MRI Fibroglandular Tissue Density or Mammographic Density.Cancer prevention research (Philadelphia, Pa.) · 2015Trial
- Correlation of Breast Density Grade on Mammogram With Diagnosed Breast Cancer: A Retrospective Cross-Sectional Study.Cureus · 2022Article
- Multimodal Patient-Specific Registration for Breast Imaging Using Biomechanical Modeling with Reference to AI Evaluation of Breast Tumor Change.Life (Basel, Switzerland) · 2021Article
- Recent advances in liposome formulations for breast cancer therapeutics.Cellular and molecular life sciences : CMLS · 2021Review
- Quantitative Mammographic Density Measurements and Molecular Subtypes in Chinese Women With Breast Cancer.JNCI cancer spectrum · 2021Article
- Evaluating the Accuracy of Breast Cancer and Molecular Subtype Diagnosis by Ultrasound Image Deep Learning Model.Frontiers in oncology · 2021Article
- Associations between mammographic density and tumor characteristics in Chinese women with breast cancer.Breast cancer research and treatment · 2019Article
- Quantitative Measurements of Breast Density Using Magnetic Resonance Imaging: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2019Review
- Imaging Breast Density: Established and Emerging Modalities.Translational oncology · 2015Review
- Breast Shape Change Associated with Aging: A Study Using Prone Breast Magnetic Resonance Imaging.Plastic and reconstructive surgery. Global open · 2015Article
- Impact of positional difference on the measurement of breast density using MRI.Medical physics · 2015Article
- Effect of taxane-based neoadjuvant chemotherapy on fibroglandular tissue volume and percent breast density in the contralateral normal breast evaluated by 3T MR.NMR in biomedicine · 2013Article
- Mammographic breast density response to aromatase inhibition.Clinical cancer research : an official journal of the American Association for Cancer Research · 2013Article
- Comparison of breast tissue measurements using magnetic resonance imaging, digital mammography and a mathematical algorithm.Physics in medicine and biology · 2012Article
- Consistency of breast density measured from the same women in four different MR scanners.Medical physics · 2012Article
- Comparison of breast density measured on MR images acquired using fat-suppressed versus nonfat-suppressed sequences.Medical physics · 2011Article
- Mammographic breast density as a risk factor for breast cancer: awareness in a recently screened clinical sample.Women's health issues : official publication of the Jacobs Institute of Women's HealthArticle
- A cross-sectional study of breast pain in a diverse population of breast cancer patients.Journal of psychosocial oncology research and practiceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
purposeThe purpose of this study was to evaluate the age- and race-dependence of the breast fibroglandular tissue density based on three-dimensional breast MRI.
methodsThe normal breasts of 321 consecutive patients including Caucasians, Asians, and Hispanics were studied. The subjects were separated into three age groups: Younger than 45, between 45 and 55, and older than 55. Computer algorithms based on body landmarks were used to segment the breast, and fuzzy c-means algorithm was used to segment the fibroglandular tissue. Linear regression analysis was applied to compare mean differences among different age groups and race/ethnicity groups. The obtained parameters were not normally distributed, and the transformed data, natural log (ln) for the fibroglandular tissue volume, and the square root for the percent density were used for statistical analysis.
resultsOn the average, the transformed fibroglandular tissue volume and percent density decreased significantly with age. Racial differences in mean transformed percent density were found among women older than 45, but not among women younger than 45. Mean percent density was higher in Asians compared to Caucasians and Hispanics; the difference remained significant after adjustment for age, but not significant after adjusted for both age and breast volume. There was no significant difference in the density between the Caucasians and the Hispanics.
conclusionsThe results analyzed using the MRI-based method show age- and race-dependence, which is consistent with literature using mammography-based methods.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.